Reaction profile

The FDA adverse-event record for extra dose(s) administered

37 FDA adverse-event reports reference extra dose(s) administered (VeDDRA 93080). See the species, breeds, and drugs most associated with it below.

37
reports citing this reaction
5.4%
death-coded share
Dog
most-affected species
Cefovecin
most-associated drug
Verify with FDA CVM →
37
Total Reports
2
Deaths
5.4%
Death Rate

Species Most Affected

Dog 26
Cat 9
Cattle 2

Breeds Most Affected

Domestic Shorthair 7
Retriever - Labrador 4
Dog (unknown) 4
Dachshund (unspecified) 3
Chihuahua 2
Shepherd Dog - German 2
Retriever - Golden 2
Shepherd Dog - Australian 2
Spaniel - Cocker English 1
Siberian Husky 1

Associated Drugs

Cefovecin 5
Milbemycin Oxime + Spinosad 4
Afoxolaner 4
Nitenpyram 3
Levothyroxine Sodium, Usp 3
Sarolaner 2
Oclacitinib Maleate 2
Meloxicam 2
Carprofen 2
Tulathromycin 2
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 1
Prednisolone 1
Anesthetic 1
Gabapentin 1
Levothyroxine Sodium 1
Robenacoxib Nsaid 1
Ketamine 1
Diazepam 1
Isoflurane 1
Ivermectin + Pyrantel 1

Extra dose(s) administered Reaction Insights

37 reports name Extra dose(s) administered; 2 recorded a death outcome (5.4% of reported events, not a population-level mortality rate). VeDDRA code: 93080.

By species: Dog (26 reports), Cat (9 reports), Cattle (2 reports). By breed: Domestic Shorthair (7), Retriever - Labrador (4), Dog (unknown) (4).

Most co-reported drugs: Cefovecin (5 reports), Milbemycin Oxime + Spinosad (4 reports), Afoxolaner (4 reports), Nitenpyram (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.