Reaction profile

The FDA adverse-event record for bloodshot eye

224 FDA adverse-event reports reference bloodshot eye (VeDDRA 1353). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#980 of 2,481
by report volume (all reactions)
224
reports citing this reaction
9.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bloodshot eye has 224 reports now versus 218 in that prior snapshot: 6 more (2.8%).

Report change
+6
Death-coded reports
+1
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bloodshot eye changes

FDA AER · VeDDRA plate

Code 1353 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 224 reports
  • DEATH-PAR 9.8%
  • MID-PACK #980/2481
  • PHOTO-FINISH Bumps on skin
  • SPECIES-DOG Dog · 208
  • DRUG-LEAD Milbemycin Oxime… · 77
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Bumps on skin (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Bloodshot eye

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site self… · near227Off colour · near225Bloodshot eye · this reaction224Bumps on skin · near224Excessive appetite · near222Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Bloodshot eye

What the FDA AER plate says about Bloodshot eye

Signature read: death-coded share at 9.8% is the most distinctive outcome stamp on Bloodshot eye. Report volume sits in the middle third of the reaction corpus. 22 of 224 reports were death-coded (9.8% of named reports, not a population mortality rate). Nearest volume peer: Bumps on skin (±0 reports). Lead species Dog (208). Lead co-reported drug Milbemycin Oxime + Spinosad (77).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 208
Human 9
Cat 5
Cattle 1
Sheep 1

Breeds Most Affected

Boxer (German Boxer) 25
Crossbred Canine/dog 21
Retriever - Labrador 21
Unknown 10
Shepherd Dog - German 10
Retriever - Golden 10
Shepherd Dog - Australian 7
Collie - Border 6
Bulldog 6
Pit Bull 5

Associated Drugs

Milbemycin Oxime + Spinosad 77
Fluralaner Chew Tablets 14
Spinosad 11
Oclacitinib Maleate 11
Moxidectin 8
Afoxolaner 8
Pyrantel Pamoate;Sarolaner 8
Trilostane 7
Carprofen 6
Milbemycin Oxime + Praziquantel 6
Fluralaner 13.64% 12-Week Chew 6
Maropitant Citrate 6
Prednisone 5
Cefovecin 5
Lotilaner 5
Fluid Therapy 5
Ivermectin + Pyrantel Pamoate 4
Phenylpropanolamine Hcl 4
Anti-Il31 Mab Mcs Lot #1283563 4
Bedinvetmab 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Bloodshot eye, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (224 here).

Similar death-coded share

Nearest other reactions by death-coded share (9.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bloodshot eye (#980 of 2,481 by report volume); death-coded 9.8%. PlainBreed reaction plate · death-coded share stamp 9.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →