Reaction profile

The FDA adverse-event record for bloodshot eye

215 FDA adverse-event reports reference bloodshot eye (VeDDRA 1353). See the species, breeds, and drugs most associated with it below.

215
reports citing this reaction
9.8%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
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215
Total Reports
21
Deaths
9.8%
Death Rate

Species Most Affected

Dog 199
Human 9
Cat 5
Cattle 1
Sheep 1

Breeds Most Affected

Boxer (German Boxer) 24
Retriever - Labrador 21
Crossbred Canine/dog 19
Unknown 10
Shepherd Dog - German 10
Retriever - Golden 9
Shepherd Dog - Australian 7
Collie - Border 6
Bulldog 6
Pit Bull 5

Associated Drugs

Milbemycin Oxime + Spinosad 77
Fluralaner Chew Tablets 14
Spinosad 11
Oclacitinib Maleate 10
Afoxolaner 8
Trilostane 7
Moxidectin 7
Pyrantel Pamoate;Sarolaner 7
Fluralaner 13.64% 12-Week Chew 6
Prednisone 5
Cefovecin 5
Carprofen 5
Milbemycin Oxime + Praziquantel 5
Maropitant Citrate 5
Ivermectin + Pyrantel Pamoate 4
Phenylpropanolamine Hcl 4
Anti-Il31 Mab Mcs Lot #1283563 4
Fluid Therapy 4
Fenbendazol Granules 3
Selamectin 3

Bloodshot eye Reaction Insights

215 reports name Bloodshot eye; 21 recorded a death outcome (9.8% of reported events, not a population-level mortality rate). VeDDRA code: 1353.

By species: Dog (199 reports), Human (9 reports), Cat (5 reports). By breed: Boxer (German Boxer) (24), Retriever - Labrador (21), Crossbred Canine/dog (19).

Most co-reported drugs: Milbemycin Oxime + Spinosad (77 reports), Fluralaner Chew Tablets (14 reports), Spinosad (11 reports), Oclacitinib Maleate (10 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.