Reaction profile

The FDA adverse-event record for nasal bleeding

349 FDA adverse-event reports reference nasal bleeding (VeDDRA 863). See the species, breeds, and drugs most associated with it below.

349
reports citing this reaction
40.4%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
349
Total Reports
141
Deaths
40.4%
Death Rate

Species Most Affected

Dog 269
Cat 51
Horse 12
Human 7
Cattle 6
Sheep 1
Rat 1
Pig 1
Marsupial 1

Breeds Most Affected

Retriever - Labrador 33
Domestic Shorthair 33
Shepherd Dog - German 21
Retriever - Golden 17
Crossbred Canine/dog 16
Unknown 10
Boxer (German Boxer) 9
Shepherd Dog - Australian 9
Shih Tzu 8
Rottweiler 8

Associated Drugs

Carprofen 36
Oclacitinib Maleate 29
Maropitant Citrate 28
Milbemycin Oxime + Spinosad 24
Bedinvetmab 24
Enrofloxacin 20
Cefovecin 18
Prednisone 18
Polysulfated Glycosaminoglycan 17
Gabapentin 16
Moxidectin 15
Spinosad 12
Trilostane 12
Doxycycline 12
Fluralaner Chew Tablets 12
Butorphanol 10
Famotidine 9
Dexamethasone 9
Diphenhydramine 9
Meloxicam 8

Nasal bleeding Reaction Insights

349 reports name Nasal bleeding; 141 recorded a death outcome (40.4% of reported events, not a population-level mortality rate). VeDDRA code: 863.

By species: Dog (269 reports), Cat (51 reports), Horse (12 reports). By breed: Retriever - Labrador (33), Domestic Shorthair (33), Shepherd Dog - German (21).

Most co-reported drugs: Carprofen (36 reports), Oclacitinib Maleate (29 reports), Maropitant Citrate (28 reports), Milbemycin Oxime + Spinosad (24 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.