Nasal bleeding

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VeDDRA Code: 863

349 adverse event reports referencing this reaction

349
Total Reports
141
Deaths
4040.0%
Death Rate

Species Most Affected

Dog 269
Cat 51
Horse 12
Human 7
Cattle 6
Sheep 1
Rat 1
Pig 1
Marsupial 1

Breeds Most Affected

Retriever - Labrador 33
Domestic Shorthair 33
Shepherd Dog - German 21
Retriever - Golden 17
Crossbred Canine/dog 16
Unknown 10
Boxer (German Boxer) 9
Shepherd Dog - Australian 9
Shih Tzu 8
Rottweiler 8

Associated Drugs

Carprofen 36
Oclacitinib Maleate 29
Maropitant Citrate 28
Milbemycin Oxime + Spinosad 24
Bedinvetmab 24
Enrofloxacin 20
Cefovecin 18
Prednisone 18
Polysulfated Glycosaminoglycan 17
Gabapentin 16
Moxidectin 15
Spinosad 12
Trilostane 12
Doxycycline 12
Fluralaner Chew Tablets 12
Butorphanol 10
Famotidine 9
Dexamethasone 9
Diphenhydramine 9
Meloxicam 8

Data Summary

Metric Value
Total reports referencing reaction 349
Reports with fatal outcome 141
Case-fatality rate (reported events) 4040.0%
Species observed 9
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 863.

Nasal bleeding Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 349 adverse event reports that reference Nasal bleeding as a reaction term, including 141 reports with a death outcome — a 4040.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 863, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Nasal bleeding appears most frequently in reports for Dog (269 reports), Cat (51 reports), Horse (12 reports) — with Dog dominating at 269 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (33), Domestic Shorthair (33), Shepherd Dog - German (21). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Nasal bleeding are Carprofen (36 reports), Oclacitinib Maleate (29 reports), Maropitant Citrate (28 reports), Milbemycin Oxime + Spinosad (24 reports), with Carprofen appearing alongside this reaction in 36 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial