Reaction profile

The FDA adverse-event record for rectal prolapse

142 FDA adverse-event reports reference rectal prolapse (VeDDRA 257). See the species, breeds, and drugs most associated with it below.

142
reports citing this reaction
42.3%
death-coded share
Cattle
most-affected species
Progesterone
most-associated drug
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142
Total Reports
60
Deaths
42.3%
Death Rate

Species Most Affected

Cattle 65
Dog 30
Pig 27
Cat 13
Horse 6
Sheep 1

Breeds Most Affected

Mixed (Cattle) 27
Crossbred Porcine/Pig 13
Cattle (other) 9
Aberdeen Angus 9
Domestic Shorthair 7
Crossbred Bovine/Cattle 6
Cattle (unknown) 5
Pig (unknown) 5
Hereford cattle 3
Crossbred Canine/dog 3

Associated Drugs

Progesterone 29
Narasin 14
Melengestrol Acetate 8
Trenbolone Acetate;Estradiol Benzoate 7
Tylosin Phosphate 6
Monensin Sodium 6
Tylosin 4
Cefovecin 4
Milbemycin Oxime + Spinosad 4
Testosterone Propionate;Estradiol Benzoate 4
Ivermectin 3
Buprenorphine 3
Meloxicam 3
Ceftiofur 3
Enrofloxacin 3
Estradiol 3
Lubabegron 3
Dexamethasone 3
Narasin Granulated 3
Praziquantel, Pyrantel Pamoate 2

Rectal prolapse Reaction Insights

142 reports name Rectal prolapse; 60 recorded a death outcome (42.3% of reported events, not a population-level mortality rate). VeDDRA code: 257.

By species: Cattle (65 reports), Dog (30 reports), Pig (27 reports). By breed: Mixed (Cattle) (27), Crossbred Porcine/Pig (13), Cattle (other) (9).

Most co-reported drugs: Progesterone (29 reports), Narasin (14 reports), Melengestrol Acetate (8 reports), Trenbolone Acetate;Estradiol Benzoate (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.