Reaction profile

The FDA adverse-event record for rectal prolapse

147 FDA adverse-event reports reference rectal prolapse (VeDDRA 257). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1203 of 2,481
by report volume (all reactions)
147
reports citing this reaction
42.9%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Rectal prolapse has 147 reports now versus 143 in that prior snapshot: 4 more (2.8%).

Report change
+4
Death-coded reports
+2
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Rectal prolapse changes

FDA AER · VeDDRA plate

Code 257 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 147 reports
  • DEATH-HOT 42.9%
  • MID-PACK #1203/2481
  • PHOTO-FINISH Active urine sediment
  • SPECIES-CATTLE Cattle · 65
  • DRUG-LEAD Progesterone · 29
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Active urine sediment (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Rectal prolapse

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Active urine sediment · near147Myelopathy NOS · near147Osteosarcoma · near147PR-PANCREAS, LESION(S) · near147Rectal prolapse · this react…147Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Rectal prolapse

Rectal prolapse: high death-coded share in the FDA AER plate

Signature read: Rectal prolapse's 42.9% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 63 of 147 reports (42.9% of named reports). Nearest volume peer: Active urine sediment (±0 reports). Lead species Cattle (65). Lead co-reported drug Progesterone (29).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 65
Dog 33
Pig 27
Cat 14
Horse 7
Sheep 1

Breeds Most Affected

Mixed (Cattle) 27
Crossbred Porcine/Pig 13
Cattle (other) 9
Aberdeen Angus 9
Domestic Shorthair 8
Crossbred Bovine/Cattle 6
Cattle (unknown) 5
Pig (unknown) 5
Hereford cattle 3
Crossbred Canine/dog 3

Associated Drugs

Progesterone 29
Narasin 14
Melengestrol Acetate 8
Trenbolone Acetate;Estradiol Benzoate 7
Tylosin Phosphate 6
Monensin Sodium 6
Tylosin 4
Cefovecin 4
Milbemycin Oxime + Spinosad 4
Testosterone Propionate;Estradiol Benzoate 4
Ivermectin 3
Meloxicam 3
Selamectin 3
Buprenorphine 3
Ceftiofur 3
Enrofloxacin 3
Estradiol 3
Lubabegron 3
Gabapentin 3
Dexamethasone 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Rectal prolapse, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (147 here).

Similar death-coded share

Nearest other reactions by death-coded share (42.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Rectal prolapse (#1203 of 2,481 by report volume); death-coded 42.9%. PlainBreed reaction plate · death-coded share stamp 42.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →