Reaction profile

The FDA adverse-event record for swollen muzzle

147 FDA adverse-event reports reference swollen muzzle (VeDDRA 2905). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1204 of 2,481
by report volume (all reactions)
147
reports citing this reaction
0.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Swollen muzzle has 147 reports now versus 128 in that prior snapshot: 19 more (14.8%).

Report change
+19
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Swollen muzzle changes

FDA AER · VeDDRA plate

Code 2905 VOL-LOW

VOL-LOW · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 147 reports
  • DEATH-RARE 0.7%
  • MID-PACK #1204/2481
  • PHOTO-FINISH Active urine sediment
  • SPECIES-DOG Dog · 136
  • DRUG-LEAD Moxidectin · 42
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Active urine sediment (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Swollen muzzle

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Active urine sediment · near147Myelopathy NOS · near147Osteosarcoma · near147PR-PANCREAS, LESION(S) · near147Swollen muzzle · this reacti…147Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Swollen muzzle

Swollen muzzle: low death-coded share in the FDA AER plate

Signature read: Swollen muzzle's 0.7% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 1 of 147 reports (0.7% of named reports). Nearest volume peer: Active urine sediment (±0 reports). Lead species Dog (136). Lead co-reported drug Moxidectin (42).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 136
Horse 10
Cat 1

Breeds Most Affected

Retriever - Labrador 13
Dachshund (unspecified) 11
Dachshund - Miniature 11
Chihuahua 10
Retriever - Golden 9
Crossbred Canine/dog 8
Shepherd Dog - Australian 6
Shepherd Dog - German 5
Terrier - Bull - American Pit 5
Mountain Dog - Bernese 4

Associated Drugs

Moxidectin 42
Rabies Vaccine 16
Pyrantel Pamoate;Sarolaner 16
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 15
Maropitant Citrate 11
Rabies Virus, Kv 11
Prednisone 9
Lotilaner 9
Oclacitinib Maleate 9
Anti-Il31 Mab Mcs Lot #1283563 9
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76;Canine Distemper Virus, Str 8
Fluralaner 13.64% 12-Week Chew 8
Bordetella Vaccine 8
Fluralaner Powder For Inj Susp 8
Ivermectin + Praziquantel 7
Milbemycin Oxime + Praziquantel 6
Diphenhydramine 6
Dexamethasone Sodium Phosphate 6
Bedinvetmab 5
Canine Influenza Virus H3N2;Canine Influenza Virus H3N8 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Swollen muzzle, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (147 here).

Similar death-coded share

Nearest other reactions by death-coded share (0.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Swollen muzzle (#1204 of 2,481 by report volume); death-coded 0.7%. PlainBreed reaction plate · death-coded share stamp 0.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →