Reaction profile

The FDA adverse-event record for cognitive and attention disorders nos

10 FDA adverse-event reports reference cognitive and attention disorders nos (VeDDRA 1381). See the species, breeds, and drugs most associated with it below.

10
reports citing this reaction
10.0%
death-coded share
Dog
most-affected species
Afoxolaner
most-associated drug
Verify with FDA CVM →
10
Total Reports
1
Deaths
10.0%
Death Rate

Species Most Affected

Dog 10

Breeds Most Affected

Poodle - Miniature 1
Retriever - Labrador 1
Terrier - Jack Russell 1
Dachshund - Standard Long-haired 1
Schnauzer - Miniature 1
Terrier - Bull - Staffordshire 1
Terrier - Rat 1
Shepherd Dog - Dutch 1
Shepherd Dog - German 1
Terrier - Bull - American Pit 1

Associated Drugs

Afoxolaner 2
Pyrantel Pamoate;Sarolaner 2
Sarolaner 2
Milbemycin Oxime + Spinosad 1
Spinosad 1
Grapiprant 1
Anthelmintic 1
Hypoallergenic Diet 1
Bedinvetmab 1
Miconazole + Polymyxin B + Prednisolone 1
Milbemycin Oxime + Praziquantel 1
Lotilaner 1
Trizedta/Ketoconazole Ear Product 1

Cognitive and attention disorders NOS Reaction Insights

10 reports name Cognitive and attention disorders NOS; 1 recorded a death outcome (10.0% of reported events, not a population-level mortality rate). VeDDRA code: 1381.

By species: Dog (10 reports). By breed: Poodle - Miniature (1), Retriever - Labrador (1), Terrier - Jack Russell (1).

Most co-reported drugs: Afoxolaner (2 reports), Pyrantel Pamoate;Sarolaner (2 reports), Sarolaner (2 reports), Milbemycin Oxime + Spinosad (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.