Reaction profile

The FDA adverse-event record for dry mucous membrane

1,154 FDA adverse-event reports reference dry mucous membrane (VeDDRA 1210). See the species, breeds, and drugs most associated with it below.

1,154
reports citing this reaction
22.6%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
1,154
Total Reports
261
Deaths
22.6%
Death Rate

Species Most Affected

Dog 1,048
Cat 94
Horse 12

Breeds Most Affected

Retriever - Labrador 107
Crossbred Canine/dog 73
Domestic Shorthair 64
Terrier - Yorkshire 48
Retriever - Golden 44
Shih Tzu 38
Shepherd Dog - German 37
Boxer (German Boxer) 36
Chihuahua 35
Dachshund (unspecified) 34

Associated Drugs

Milbemycin Oxime + Spinosad 191
Carprofen 139
Maropitant Citrate 132
Moxidectin 118
Gabapentin 52
Spinosad 49
Enrofloxacin 48
Fluralaner Chew Tablets 48
Afoxolaner 47
Buprenorphine 45
Deracoxib 44
Trilostane 42
Tramadol 39
Famotidine 39
Ivermectin + Pyrantel As Pamoate Salt 37
Metronidazole 36
Oclacitinib Maleate 35
Prednisone 34
Milbemycin Oxime + Praziquantel 34
Bedinvetmab 34

Dry mucous membrane Reaction Insights

1,154 reports name Dry mucous membrane; 261 recorded a death outcome (22.6% of reported events, not a population-level mortality rate). VeDDRA code: 1210.

By species: Dog (1,048 reports), Cat (94 reports), Horse (12 reports). By breed: Retriever - Labrador (107), Crossbred Canine/dog (73), Domestic Shorthair (64).

Most co-reported drugs: Milbemycin Oxime + Spinosad (191 reports), Carprofen (139 reports), Maropitant Citrate (132 reports), Moxidectin (118 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.