Reaction profile

The FDA adverse-event record for implant site swelling

26 FDA adverse-event reports reference implant site swelling (VeDDRA 56). See the species, breeds, and drugs most associated with it below.

26
reports citing this reaction
3.8%
death-coded share
Dog
most-affected species
Deslorelin Acetate
most-associated drug
Verify with FDA CVM →
26
Total Reports
1
Deaths
3.8%
Death Rate

Species Most Affected

Dog 13
Ferret 6
Cattle 3
Cat 3
Horse 1

Breeds Most Affected

Dog (unknown) 5
Unknown 4
Mixed (Cattle) 3
Domestic ferret (Pet ferret) 2
Doberman Pinscher 1
Terrier (unspecified) 1
Cat (unknown) 1
Domestic Shorthair 1
Pit Bull 1
Saint Bernard Dog 1

Associated Drugs

Deslorelin Acetate 4
Gabapentin 3
Carprofen 2
Device: Suture 2
Deslorelin 2
Trenbolone Acetate;Estradiol Benzoate 2
Bedinvetmab 2
Grapiprant 2
Oclacitinib Maleate 2
Canine Interleukin-31 Monoclonal Antibody 2
Sedative (Unknown) 2
Tramadol 2
Glycosaminoglycan Polysulfate 1
Device: Surgical Instruments 1
Progesterone; Estradiol Benzoate 1
Moxidectin 1
Cefovecin 1
Melarsomine Dihydrochloride 1
Afoxolaner 1
Ivermectin + Praziquantel 1

Implant site swelling Reaction Insights

26 reports name Implant site swelling; 1 recorded a death outcome (3.8% of reported events, not a population-level mortality rate). VeDDRA code: 56.

By species: Dog (13 reports), Ferret (6 reports), Cattle (3 reports). By breed: Dog (unknown) (5), Unknown (4), Mixed (Cattle) (3).

Most co-reported drugs: Deslorelin Acetate (4 reports), Gabapentin (3 reports), Carprofen (2 reports), Device: Suture (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.