Reaction profile

The FDA adverse-event record for implant site swelling

26 FDA reports name implant site swelling, a lower-volume reaction in the CVM extract (VeDDRA 56). Plate stamps and neighbourhood peers follow.

#2055 of 2,481
by report volume (all reactions)
26
reports citing this reaction
3.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Implant site swelling has 26 reports now versus 26 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Implant site swelling changes

FDA AER · VeDDRA plate

Code 56 VOL-TRACE

VOL-TRACE · DEATH-LOW · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 26 reports
  • DEATH-LOW 3.8%
  • LOWER-Q #2055/2481
  • PHOTO-FINISH Cushings disease - pi…
  • SPECIES-DOG Dog · 13
  • DRUG-LEAD Deslorelin Acetate · 4
  • DESK-WIDE 16 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cushings disease - pituitary dependent (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Implant site swelling

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Cushings disease - pi… · near26Dermoid cyst · near26Feet shifting · near26Haemorrhagic gastritis · near26Implant site swelling · this…26Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Implant site swelling

Implant site swelling: low death-coded share in the FDA AER plate

Signature read: 1 death-coded reports is a thin tail count for Implant site swelling in the CVM extract. Report volume is lower-third scale: 26 named reports in the openFDA extract. Death-coded share is lower-third: 1 of 26 reports (3.8% of named reports). Nearest volume peer: Cushings disease - pituitary dependent (±0 reports). Lead species Dog (13). Lead co-reported drug Deslorelin Acetate (4).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Deslorelin Acetate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 13
Ferret 6
Cattle 3
Cat 3
Horse 1

Breeds Most Affected

Dog (unknown) 5
Unknown 4
Mixed (Cattle) 3
Domestic ferret (Pet ferret) 2
Doberman Pinscher 1
Terrier (unspecified) 1
Cat (unknown) 1
Domestic Shorthair 1
Pit Bull 1
Saint Bernard Dog 1

Associated Drugs

Deslorelin Acetate 4
Gabapentin 3
Carprofen 2
Device: Suture 2
Deslorelin 2
Trenbolone Acetate;Estradiol Benzoate 2
Grapiprant 2
Oclacitinib Maleate 2
Canine Interleukin-31 Monoclonal Antibody 2
Sedative (Unknown) 2
Tramadol 2
Bedinvetmab 2
Glycosaminoglycan Polysulfate 1
Device: Surgical Instruments 1
Progesterone; Estradiol Benzoate 1
Moxidectin 1
Cefovecin 1
Melarsomine Dihydrochloride 1
Ivermectin + Praziquantel 1
Afoxolaner 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Implant site swelling (#2055 of 2,481 by report volume); death-coded 3.8%. PlainBreed reaction plate · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →