Reaction profile

The FDA adverse-event record for gall stone

44 FDA adverse-event reports reference gall stone (VeDDRA 1487). See the species, breeds, and drugs most associated with it below.

44
reports citing this reaction
15.9%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
44
Total Reports
7
Deaths
15.9%
Death Rate

Species Most Affected

Dog 35
Cat 8
Human 1

Breeds Most Affected

Domestic Shorthair 5
Terrier - Yorkshire 3
Crossbred Canine/dog 3
Chihuahua 3
Shih Tzu 3
Retriever - Labrador 3
Spaniel - King Charles Cavalier 2
Dachshund - Miniature 2
Shepherd Dog - German 2
Beagle 2

Associated Drugs

Milbemycin Oxime + Spinosad 6
Carprofen 6
Trilostane 5
Metronidazole 3
Cefovecin 3
Maropitant Citrate 3
Bexagliflozin 3
Enrofloxacin 2
Ivermectin 2
Grapiprant 2
Milbemycin Oxime + Praziquantel 2
Injectable Analgesic 2
Gabapentin 2
Amoxicillin 2
Prescription Diet 2
Velagliflozin Proline Monohydrate 2
Bedinvetmab 2
Imidacloprid + Moxidectin 1
Imidacloprid + Permethrin + Pyriproxyfen 1
Hydromorphone 1

Gall stone Reaction Insights

44 reports name Gall stone; 7 recorded a death outcome (15.9% of reported events, not a population-level mortality rate). VeDDRA code: 1487.

By species: Dog (35 reports), Cat (8 reports), Human (1 reports). By breed: Domestic Shorthair (5), Terrier - Yorkshire (3), Crossbred Canine/dog (3).

Most co-reported drugs: Milbemycin Oxime + Spinosad (6 reports), Carprofen (6 reports), Trilostane (5 reports), Metronidazole (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.