Reaction profile

The FDA adverse-event record for polypnoea

1,224 FDA reports name polypnoea, a high-volume reaction in the CVM extract (VeDDRA 857). Plate stamps and neighbourhood peers follow.

#337 of 2,481
by report volume (all reactions)
1,224
reports citing this reaction
14.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Polypnoea has 1,224 reports now versus 1,223 in that prior snapshot: 1 more (0.1%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Polypnoea changes

FDA AER · VeDDRA plate

Code 857 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,224 reports
  • DEATH-ELEV 14.2%
  • UPPER-Q #337/2481
  • PHOTO-FINISH Dry mucous membrane
  • SPECIES-DOG Dog · 1,048
  • DRUG-LEAD Melarsomine Dihyd… · 150
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Dry mucous membrane (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Polypnoea

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Pneumonia · near1230INEFFECTIVE, SEDATION · near1229Dry mucous membrane · near1224Hypersensitivity reac… · near1224Polypnoea · this reaction1224Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Polypnoea

What the FDA AER plate says about Polypnoea

Signature read: 174 death-coded reports is a heavy tail count for Polypnoea in the CVM extract. Report volume is upper-third scale: 1,224 named reports in the openFDA extract. 174 of 1,224 reports were death-coded (14.2% of named reports, not a population mortality rate). Nearest volume peer: Dry mucous membrane (±0 reports). Lead species Dog (1,048). Lead co-reported drug Melarsomine Dihydrochloride (150).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Melarsomine Dihydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,048
Cat 161
Horse 5
Cattle 5
Goat 2
Sheep 1
Other Deer 1
Rabbit 1

Breeds Most Affected

Crossbred Canine/dog 258
Domestic (unspecified) 134
Retriever - Labrador 100
Retriever - Golden 39
Dog (unknown) 35
Shepherd Dog - German 35
Terrier - Yorkshire 31
Shih Tzu 30
Boxer (German Boxer) 26
Shepherd Dog - Australian 24

Associated Drugs

Melarsomine Dihydrochloride 150
Spinosad 103
Cyclosporine 103
Carprofen 84
Nitenpyram 76
Ivermectin, Pyrantel 63
Deracoxib 50
Selamectin 44
Imidacloprid, Moxidectin 41
Spinosad, Milbemycin 39
Milbemycin 33
Meloxicam 31
Firocoxib 29
Moxidectin 22
Atipamezole 21
Cefovecin Sodium 21
Dexmedetomidine Hydrochloride 19
Milbemycin, Lufenuron 16
Pimobendan 15
Maropitant 13

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Polypnoea, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,224 here).

Similar death-coded share

Nearest other reactions by death-coded share (14.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Polypnoea (#337 of 2,481 by report volume); death-coded 14.2%. PlainBreed reaction plate · death-coded report count stamp 174 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →