Reaction profile

The FDA adverse-event record for decreased ruminal activity

12 FDA adverse-event reports reference decreased ruminal activity (VeDDRA 2619). See the species, breeds, and drugs most associated with it below.

12
reports citing this reaction
50.0%
death-coded share
Cattle
most-affected species
Monensin Sodium
most-associated drug
Verify with FDA CVM →
12
Total Reports
6
Deaths
50.0%
Death Rate

Species Most Affected

Cattle 11
Goat 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 11
Boer 1

Associated Drugs

Monensin Sodium 5
Eprinomectin 4
Cloxacillin Benzathine 1
Bismuth Subnitrate 60% Intramammary 1
Ceftiofur Hydrochloride 1
Clostridium Perfringens Type C Bacterin-Toxoid;Bovine Rotavirus, Bk-3 Lot 6 Linc 1
E. Coli Strain J5, Lot #072692 1
Dinoprost Tromethamine 1
Bacillus Licheniformis Fermentation Exctract 1
Calcium 1

Decreased ruminal activity Reaction Insights

12 reports name Decreased ruminal activity; 6 recorded a death outcome (50.0% of reported events, not a population-level mortality rate). VeDDRA code: 2619.

By species: Cattle (11 reports), Goat (1 reports). By breed: Holstein-Friesian also known as Holstein (11), Boer (1).

Most co-reported drugs: Monensin Sodium (5 reports), Eprinomectin (4 reports), Cloxacillin Benzathine (1 reports), Bismuth Subnitrate 60% Intramammary (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.