Reaction profile

The FDA adverse-event record for decreased ruminal activity

14 FDA reports name decreased ruminal activity, a lower-volume reaction in the CVM extract (VeDDRA 2619). Plate stamps and neighbourhood peers follow.

#2324 of 2,481
by report volume (all reactions)
14
reports citing this reaction
42.9%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Decreased ruminal activity has 14 reports now versus 12 in that prior snapshot: 2 more (16.7%).

Report change
+2
Death-coded reports
+0
Death-coded share
−7.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Decreased ruminal activity changes

FDA AER · VeDDRA plate

Code 2619 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-NARROW · BOOK-FULL

  • VOL-TRACE 14 reports
  • DEATH-HOT 42.9%
  • BOTTOM-DECILE #2324/2481
  • PHOTO-FINISH Addisonian crisis
  • SPECIES-CATTLE Cattle · 13
  • DRUG-LEAD Monensin Sodium · 7
  • DESK-NARROW 2 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Addisonian crisis (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Decreased ruminal activity

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Addisonian crisis · near14Application site puru… · near14Bullous disorder NOS · near14Chapped skin · near14Decreased ruminal act… · thi…14Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Decreased ruminal activity

Decreased ruminal activity: high death-coded share in the FDA AER plate

Signature read: 14 reports place Decreased ruminal activity in the lower third of FDA AER volume (#2324 of 2,481). Report volume is lower-third scale: 14 named reports in the openFDA extract. Death-coded share is upper-third: 6 of 14 reports (42.9% of named reports). Nearest volume peer: Addisonian crisis (±0 reports). Lead species Cattle (13). Lead co-reported drug Monensin Sodium (7).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 13
Goat 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 13
Boer 1

Associated Drugs

Monensin Sodium 7
Eprinomectin 4
Cloxacillin Benzathine 1
Bismuth Subnitrate 60% Intramammary 1
Ceftiofur Hydrochloride 1
Clostridium Perfringens Type C Bacterin-Toxoid;Bovine Rotavirus, Bk-3 Lot 6 Linc 1
E. Coli Strain J5, Lot #072692 1
Bacillus Licheniformis Fermentation Exctract 1
Dinoprost Tromethamine 1
Calcium 1
3-Nitrooxypropanol 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decreased ruminal activity (#2324 of 2,481 by report volume); death-coded 42.9%. PlainBreed reaction plate · report volume stamp 14 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →