Reaction profile

The FDA adverse-event record for skin and/or appendage neoplasm nos

289 FDA adverse-event reports reference skin and/or appendage neoplasm nos (VeDDRA 922). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#885 of 2,481
by report volume (all reactions)
289
reports citing this reaction
13.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Skin and/or appendage neoplasm NOS has 289 reports now versus 286 in that prior snapshot: 3 more (1.0%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Skin and/or appendage neoplasm NOS changes

FDA AER · VeDDRA plate

Code 922 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 289 reports
  • DEATH-ELEV 13.1%
  • MID-PACK #885/2481
  • PHOTO-FINISH Application site derm…
  • SPECIES-DOG Dog · 270
  • DRUG-LEAD Oclacitinib Malea… · 135
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site dermatitis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Skin and/or appendage neoplasm NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site derm… · near289Difficulty going up/d… · near289Haemoconcentration · near289Product syringe calib… · near289Skin and/or appendage… · thi…289Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Skin and/or appendage neoplasm NOS

What the FDA AER plate says about Skin and/or appendage neoplasm NOS

Signature read: 38 death-coded reports is the most distinctive absolute-outcome stamp on Skin and/or appendage neoplasm NOS. Report volume sits in the middle third of the reaction corpus. 38 of 289 reports were death-coded (13.1% of named reports, not a population mortality rate). Nearest volume peer: Application site dermatitis (±0 reports). Lead species Dog (270). Lead co-reported drug Oclacitinib Maleate (135).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 270
Cat 19

Breeds Most Affected

Retriever - Labrador 36
Retriever - Golden 20
Terrier - Bull - American Pit 16
Crossbred Canine/dog 15
Boxer (German Boxer) 13
Beagle 11
Shih Tzu 9
Shepherd Dog - German 9
Domestic (unspecified) 7
Lhasa Apso 7

Associated Drugs

Oclacitinib Maleate 135
Cyclosporine 45
Cyclosporine A 34
Milbemycin Oxime + Spinosad 26
Anti-Il31 Mab Mcs Lot #1283563 14
Carprofen 12
Trilostane 12
Prednisone 10
Cefpodoxime Proxetil 9
Cefovecin Sodium 8
Cephalexin 8
Ketoconazole 6
Gabapentin 6
Enrofloxacin 5
Spinosad 5
Cefovecin 5
Ivermectin 5
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 5
Afoxolaner 5
Anesthetic 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Skin and/or appendage neoplasm NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (13.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Skin and/or appendage neoplasm NOS (#885 of 2,481 by report volume); death-coded 13.1%. PlainBreed reaction plate · death-coded report count stamp 38 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →