Reaction profile

The FDA adverse-event record for nt - hepatic or biliary tumour (hepatocarcinoma/cholangiocarcinoma/ adenoma/cholangioma)

10 FDA adverse-event reports reference nt - hepatic or biliary tumour (hepatocarcinoma/cholangiocarcinoma/ adenoma/cholangioma) (VeDDRA 2329). See the species, breeds, and drugs most associated with it below.

10
reports citing this reaction
70.0%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
10
Total Reports
7
Deaths
70.0%
Death Rate

Species Most Affected

Dog 9
Cat 1

Breeds Most Affected

Retriever - Labrador 2
Beagle 1
Shih Tzu 1
Spaniel - Cocker American 1
Chow Chow 1
Collie (unspecified) 1
Domestic Shorthair 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Schnauzer (unspecified) 1

Associated Drugs

Trilostane 3
Oclacitinib Maleate 2
Polysulfated Glycosaminoglycan 2
Probiotic 1
Bordetella Bronchiseptica, Strain 78-9159, Kb 1
Afoxolaner 1
Ivermectin + Pyrantel As Pamoate Salt 1
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 1
Cyclosporine 1
Anesthesia 1
Contrast Agent 1
Squalane 1
Sterile Saline 1
Steroid 1
Fluralaner Chew Tablets 1
Da2Ppv+L*4 (Orig S-P Us) Lv+Kb 1

NT - hepatic or biliary tumour (hepatocarcinoma/cholangiocarcinoma/ adenoma/cholangioma) Reaction Insights

10 reports name NT - hepatic or biliary tumour (hepatocarcinoma/cholangiocarcinoma/ adenoma/cholangioma); 7 recorded a death outcome (70.0% of reported events, not a population-level mortality rate). VeDDRA code: 2329.

By species: Dog (9 reports), Cat (1 reports). By breed: Retriever - Labrador (2), Beagle (1), Shih Tzu (1).

Most co-reported drugs: Trilostane (3 reports), Oclacitinib Maleate (2 reports), Polysulfated Glycosaminoglycan (2 reports), Probiotic (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.