Reaction profile

The FDA adverse-event record for lack of efficacy (ectoparasite) - fly

25 FDA reports name lack of efficacy (ectoparasite) - fly, a lower-volume reaction in the CVM extract (VeDDRA 2650). Plate stamps and neighbourhood peers follow.

#2073 of 2,481
by report volume (all reactions)
25
reports citing this reaction
0.0%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (ectoparasite) - fly has 25 reports now versus 25 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (ectoparasite) - fly changes

FDA AER · VeDDRA plate

Code 2650 VOL-TRACE

VOL-TRACE · DEATH-RARE · LOWER-Q · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 25 reports
  • DEATH-RARE 0.0%
  • LOWER-Q #2073/2481
  • PHOTO-FINISH Abnormal behaviour NOS
  • SPECIES-CATTLE Cattle · 14
  • DRUG-LEAD Moxidectin · 9
  • DESK-WIDE 15 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal behaviour NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy - fly

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal behaviour NOS · near25Buccal ulceration · near25Dizzy spell · near25Elevated serum lipids · near25Lack of efficacy (ect… · thi…25Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (ectoparasite) - fly

Lack of efficacy (ectoparasite) - fly: low death-coded share in the FDA AER plate

Signature read: Lack of efficacy (ectoparasite) - fly's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 25 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 25 reports (0.0% of named reports). Nearest volume peer: Abnormal behaviour NOS (±0 reports). Lead species Cattle (14). Lead co-reported drug Moxidectin (9).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 14
Dog 5
Cat 3
Horse 3

Breeds Most Affected

Cattle (unknown) 3
Cattle (other) 3
Mixed (Cattle) 3
Crossbred Bovine/Cattle 2
Aberdeen Angus 2
Quarter Horse 2
Boxer (German Boxer) 2
Retriever - Labrador 1
Cat (other) 1
Shepherd Dog - German 1

Associated Drugs

Moxidectin 9
Pyrantel Pamoate;Sarolaner 3
Omeprazole 3
Ivermectin 2
Eprinomectin 2
Cyfluthrin 2
Fluralaner Chew Tablets 1
Selamectin 1
Fluralaner 13.64% 12-Week Chew 1
Doramectin 1
Beta-Cyfluthrin + Pbo 1
Pyrantel Embonate, Praziquantel 1
Selamectin,Sarolaner 1
Tetrachlorvinphos 1
Permethrin, Diflubenzuron 1
Dewormer (Unknown) 1
Unknown Medication 1
Propoxur,Pyriproxyfen,Lambda-Cyhalothrin 1
Nitenpyram 1
Liquid Dish Soap 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (ectoparasite) - fly (#2073 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →