Reaction profile

The FDA adverse-event record for fear/fearful

130 FDA adverse-event reports reference fear/fearful (VeDDRA 3062). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1262 of 2,481
by report volume (all reactions)
130
reports citing this reaction
7.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Fear/fearful has 130 reports now versus 108 in that prior snapshot: 22 more (20.4%).

Report change
+22
Death-coded reports
+2
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Fear/fearful changes

FDA AER · VeDDRA plate

Code 3062 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 130 reports
  • DEATH-PAR 7.7%
  • MID-PACK #1262/2481
  • PHOTO-FINISH Eye inflammation NOS
  • SPECIES-DOG Dog · 98
  • DRUG-LEAD Buprenorphine · 16
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Eye inflammation NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Fear/fearful

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cold feeling to the t… · near131Eye inflammation NOS · near130Fear/fearful · this reaction130Missing component, me… · near130Moribund · near130Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Fear/fearful

Fear/fearful: low death-coded share in the FDA AER plate

Signature read: Fear/fearful's 7.7% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 10 of 130 reports (7.7% of named reports). Nearest volume peer: Eye inflammation NOS (±0 reports). Lead species Dog (98). Lead co-reported drug Buprenorphine (16).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Buprenorphine appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 98
Cat 31
Horse 1

Breeds Most Affected

Domestic Shorthair 17
Retriever - Labrador 7
Shepherd Dog - German 6
Dog (unknown) 6
Crossbred Canine/dog 6
Chihuahua 5
Retriever - Golden 4
Terrier - Yorkshire 3
Cat (unknown) 3
Domestic Longhair 3

Associated Drugs

Buprenorphine 16
Pyrantel Pamoate;Sarolaner 13
Bedinvetmab 12
Milbemycin Oxime + Praziquantel 11
Lotilaner 8
Gabapentin 8
Fluralaner 13.64% 12-Week Chew 7
Sarolaner 7
Afoxolaner 7
Ivermectin + Pyrantel As Pamoate Salt 6
Maropitant Citrate 5
Sedative (Unknown) 5
Selamectin;Sarolaner 5
Cefovecin Sodium 4
Afoxolaner 150Mg / Moxidectin 720Mcg / Pyrantel 300Mg Chewable Tablet 4
Carprofen 4
Milbemycin Oxime 3
Fluralaner 3
Afoxolaner 37.5Mg / Moxidectin 180Mcg / Pyrantel 75Mg Chewable Tablet 3
Trazodone 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Fear/fearful, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (130 here).

Similar death-coded share

Nearest other reactions by death-coded share (7.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Fear/fearful (#1262 of 2,481 by report volume); death-coded 7.7%. PlainBreed reaction plate · death-coded share stamp 7.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →