Reaction profile

The FDA adverse-event record for abnormal urine odour

337 FDA adverse-event reports reference abnormal urine odour (VeDDRA 1966). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#826 of 2,481
by report volume (all reactions)
337
reports citing this reaction
9.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Abnormal urine odour has 337 reports now versus 333 in that prior snapshot: 4 more (1.2%).

Report change
+4
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Abnormal urine odour changes

FDA AER · VeDDRA plate

Code 1966 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 337 reports
  • DEATH-PAR 9.8%
  • MID-PACK #826/2481
  • PHOTO-FINISH Hyperextension
  • SPECIES-DOG Dog · 282
  • DRUG-LEAD Imidacloprid + Mo… · 76
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hyperextension (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Abnormal urine odour

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Hypersensitivity NOS · near339Abnormal urine odour · this …337Hyperextension · near337Crackles on auscultat… · near335Urolithiasis · near335Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Abnormal urine odour

What the FDA AER plate says about Abnormal urine odour

Signature read: 337 reports place Abnormal urine odour in the upper third of FDA AER volume (#826 of 2,481). Report volume sits in the middle third of the reaction corpus. 33 of 337 reports were death-coded (9.8% of named reports, not a population mortality rate). Nearest volume peer: Hyperextension (±0 reports). Lead species Dog (282). Lead co-reported drug Imidacloprid + Moxidectin (76).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Imidacloprid + Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 282
Cat 47
Horse 5
Human 1
Other Rodents 1
Unknown 1

Breeds Most Affected

Domestic Shorthair 30
Retriever - Labrador 27
Chihuahua 19
Crossbred Canine/dog 18
Shih Tzu 17
Maltese 12
Boxer (German Boxer) 10
Terrier - Yorkshire 10
Dachshund (unspecified) 8
Retriever - Golden 8

Associated Drugs

Imidacloprid + Moxidectin 76
Trilostane 37
Milbemycin Oxime + Spinosad 27
Carprofen 26
Bedinvetmab 24
Afoxolaner 14
Cyclosporine 10
Meloxicam 9
Cefovecin 9
Oclacitinib Maleate 8
Maropitant Citrate 8
Bexagliflozin 8
Imidacloprid, Moxidectin 7
Gabapentin 7
Firocoxib 6
Deracoxib 6
Spinosad 6
Prednisone 6
Cyclosporine A 5
Famotidine 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Abnormal urine odour, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (337 here).

Similar death-coded share

Nearest other reactions by death-coded share (9.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Abnormal urine odour (#826 of 2,481 by report volume); death-coded 9.8%. PlainBreed reaction plate · report volume stamp 337 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →