Reaction profile

The FDA adverse-event record for anal oedema

23 FDA reports name anal oedema, a lower-volume reaction in the CVM extract (VeDDRA 2239). Plate stamps and neighbourhood peers follow.

#2102 of 2,481
by report volume (all reactions)
23
reports citing this reaction
4.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Anal oedema has 23 reports now versus 23 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Anal oedema changes

FDA AER · VeDDRA plate

Code 2239 VOL-TRACE

VOL-TRACE · DEATH-LOW · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 23 reports
  • DEATH-LOW 4.3%
  • LOWER-Q #2102/2481
  • PHOTO-FINISH Boil
  • SPECIES-DOG Dog · 18
  • DRUG-LEAD Praziquantel, Pyr… · 2
  • DESK-WIDE 16 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Boil (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Anal oedema

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Anal oedema · this reaction23Boil · near23Cervical spondylopathy · near23Chewing at injection… · near23CORTISOL:CREATININE H… · near23Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Anal oedema

Anal oedema: low death-coded share in the FDA AER plate

Signature read: 1 death-coded reports is a thin tail count for Anal oedema in the CVM extract. Report volume is lower-third scale: 23 named reports in the openFDA extract. Death-coded share is lower-third: 1 of 23 reports (4.3% of named reports). Nearest volume peer: Boil (±0 reports). Lead species Dog (18). Lead co-reported drug Praziquantel, Pyrantel Pamoate (2).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Praziquantel, Pyrantel Pamoate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 18
Pig 2
Cat 1
Horse 1
Cattle 1

Breeds Most Affected

Shih Tzu 4
Beagle 2
Crossbred Canine/dog 2
Crossbred Porcine/Pig 2
Dog (unknown) 2
Domestic (unspecified) 1
Spitz - German Pomeranian 1
Chihuahua 1
Maltese 1
Bulldog 1

Associated Drugs

Praziquantel, Pyrantel Pamoate 2
Carprofen 2
Fenbendazol Granules 2
Milbemycin, Lufenuron 1
Cefovecin Sodium 1
Amoxicillin, Clavulanate 1
Nitenpyram 1
Cyclosporine 1
Lincomycin Hydrochloride 1
Florfenicol 1
Ivermectin + Pyrantel As Pamoate Salt 1
Fluralaner Chew Tablets 1
Afoxolaner 1
Afoxolaner 136 Mg Chewable Tablets 1
Polysulfated Glycosaminoglycan 1
Polyvinyl Alcohol/Povidone 1
Mineral Oil 1
Sucralfate 1
Furosemide 1
Benazepril 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Anal oedema (#2102 of 2,481 by report volume); death-coded 4.3%. PlainBreed reaction plate · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →