Reaction profile

The FDA adverse-event record for anal oedema

20 FDA adverse-event reports reference anal oedema (VeDDRA 2239). See the species, breeds, and drugs most associated with it below.

20
reports citing this reaction
5.0%
death-coded share
Dog
most-affected species
Praziquantel, Pyrantel Pamoate
most-associated drug
Verify with FDA CVM →
20
Total Reports
1
Deaths
5.0%
Death Rate

Species Most Affected

Dog 16
Pig 2
Cat 1
Horse 1

Breeds Most Affected

Shih Tzu 4
Beagle 2
Crossbred Canine/dog 2
Crossbred Porcine/Pig 2
Dog (unknown) 2
Spitz - German Pomeranian 1
Domestic (unspecified) 1
Maltese 1
Chihuahua 1
Bulldog 1

Associated Drugs

Praziquantel, Pyrantel Pamoate 2
Fenbendazol Granules 2
Cefovecin Sodium 1
Milbemycin, Lufenuron 1
Carprofen 1
Amoxicillin, Clavulanate 1
Cyclosporine 1
Nitenpyram 1
Lincomycin Hydrochloride 1
Florfenicol 1
Ivermectin + Pyrantel As Pamoate Salt 1
Fluralaner Chew Tablets 1
Afoxolaner 1
Polysulfated Glycosaminoglycan 1
Polyvinyl Alcohol/Povidone 1
Mineral Oil 1
Sucralfate 1
Furosemide 1
Benazepril 1
E.Thermophiles, L. Acidophilus, B Longum, Psyllium Husk 1

Anal oedema Reaction Insights

20 reports name Anal oedema; 1 recorded a death outcome (5.0% of reported events, not a population-level mortality rate). VeDDRA code: 2239.

By species: Dog (16 reports), Pig (2 reports), Cat (1 reports). By breed: Shih Tzu (4), Beagle (2), Crossbred Canine/dog (2).

Most co-reported drugs: Praziquantel, Pyrantel Pamoate (2 reports), Fenbendazol Granules (2 reports), Cefovecin Sodium (1 reports), Milbemycin, Lufenuron (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.