Intention tremor

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VeDDRA Code: 2249

88 adverse event reports referencing this reaction

88
Total Reports
9
Deaths
1020.0%
Death Rate

Species Most Affected

Dog 65
Cat 23

Breeds Most Affected

Domestic Shorthair 16
Retriever - Labrador 7
Shepherd Dog - German 4
Shepherd Dog - Australian 4
Chihuahua 4
Retriever - Golden 3
Deutsche Dogge, Great Dane 3
Maine Coon 2
Dachshund (unspecified) 2
Cat (unknown) 2

Associated Drugs

Carprofen 11
Maropitant Citrate 9
Afoxolaner 8
Fluralaner Chew Tablets 6
Sarolaner 6
Selamectin 5
Milbemycin Oxime + Spinosad 5
Milbemycin Oxime + Praziquantel 5
Fluralaner Spot-On Solution 5
Isoflurane 5
Lotilaner 5
Ivermectin + Pyrantel As Pamoate Salt 4
Moxidectin 4
Oclacitinib Maleate 4
Spinosad 4
Pyrantel Pamoate;Sarolaner 4
Bedinvetmab 4
Betamethasone + Florfenicol + Terbinafine 3
Buprenorphine 3
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 3

Data Summary

Metric Value
Total reports referencing reaction 88
Reports with fatal outcome 9
Case-fatality rate (reported events) 1020.0%
Species observed 2
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2249.

Intention tremor Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 88 adverse event reports that reference Intention tremor as a reaction term, including 9 reports with a death outcome — a 1020.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2249, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Intention tremor appears most frequently in reports for Dog (65 reports), Cat (23 reports) — with Dog dominating at 65 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (16), Retriever - Labrador (7), Shepherd Dog - German (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Intention tremor are Carprofen (11 reports), Maropitant Citrate (9 reports), Afoxolaner (8 reports), Fluralaner Chew Tablets (6 reports), with Carprofen appearing alongside this reaction in 11 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial