Reaction profile

The FDA adverse-event record for premature parturition

30 FDA adverse-event reports reference premature parturition (VeDDRA 787). See the species, breeds, and drugs most associated with it below.

30
reports citing this reaction
33.3%
death-coded share
Cattle
most-affected species
Pegbovigrastim
most-associated drug
Verify with FDA CVM →
30
Total Reports
10
Deaths
33.3%
Death Rate

Species Most Affected

Cattle 14
Dog 13
Goat 1
Cat 1
Pig 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 9
Terrier - Yorkshire 3
Cattle (unknown) 3
Spaniel - King Charles Cavalier 2
Spitz - German Pomeranian 1
Crossbred Canine/dog 1
Brown Swiss 1
Collie - Smooth-haired 1
Shepherd Dog - German 1
Rottweiler 1

Associated Drugs

Pegbovigrastim 7
Monensin Sodium 4
Milbemycin Oxime + Spinosad 4
Spinosad 2
Fluralaner Chew Tablets 2
Maropitant 1
Novobiocin, Penicillin G Procaine 1
Eprinomectin 1
Fenbendazole 1
Vitamins 1
Afoxolaner 2.27% Chewable Tablet (136 Mg) 1
Sometribove 1
Kibr + Kbvd + Pi3 + Brsv + Lepto 5 Hb 1
Escherichia Coli Bacterin 1
Staphylococcus Aureus Bacterin 1
Ivermectin 10 Mg/Ml Solution For Injection 1
Afoxolaner 1
Vitamin A + Vitamin D3 + Vitamin E 1
Vaccines (Unknown) 1
Tulathromycin 1

Premature parturition Reaction Insights

30 reports name Premature parturition; 10 recorded a death outcome (33.3% of reported events, not a population-level mortality rate). VeDDRA code: 787.

By species: Cattle (14 reports), Dog (13 reports), Goat (1 reports). By breed: Holstein-Friesian also known as Holstein (9), Terrier - Yorkshire (3), Cattle (unknown) (3).

Most co-reported drugs: Pegbovigrastim (7 reports), Monensin Sodium (4 reports), Milbemycin Oxime + Spinosad (4 reports), Spinosad (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.