Uraemia

Uraemia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 23 adverse event reports that reference Uraemia as a reaction term, including 17 reports with a death outcome — a 7390.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 722, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Uraemia appears most frequently in reports for Dog (19 reports), Cat (4 reports) — with Dog dominating at 19 entries. Within those species, the breeds most often named alongside this reaction are Chihuahua (2), Domestic Shorthair (2), Cat (unknown) (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Uraemia are Meloxicam (4 reports), Carprofen (3 reports), Trilostane (3 reports), Deracoxib (2 reports), with Meloxicam appearing alongside this reaction in 4 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.