Reaction profile

The FDA adverse-event record for respiratory tract disorder nos

945 FDA reports name respiratory tract disorder nos, a high-volume reaction in the CVM extract (VeDDRA 1180). Plate stamps and neighbourhood peers follow.

#409 of 2,481
by report volume (all reactions)
945
reports citing this reaction
48.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Respiratory tract disorder NOS has 945 reports now versus 943 in that prior snapshot: 2 more (0.2%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Respiratory tract disorder NOS changes

FDA AER · VeDDRA plate

Code 1180 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 945 reports
  • DEATH-HOT 48.7%
  • UPPER-Q #409/2481
  • PHOTO-FINISH Urinary tract disorde…
  • SPECIES-DOG Dog · 499
  • DRUG-LEAD Milbemycin Oxime… · 69
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Urinary tract disorder NOS (±2 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Respiratory tract disorder NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Haematochezia · near948Respiratory tract dis… · thi…945Urinary tract disorde… · near943Grand mal seizure · near942Drug administration d… · near938Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Respiratory tract disorder NOS

Respiratory tract disorder NOS: high death-coded share in the FDA AER plate

Signature read: 460 death-coded reports is a heavy tail count for Respiratory tract disorder NOS in the CVM extract. Report volume is upper-third scale: 945 named reports in the openFDA extract. Death-coded share is upper-third: 460 of 945 reports (48.7% of named reports). Nearest volume peer: Urinary tract disorder NOS (±2 reports). Lead species Dog (499). Lead co-reported drug Milbemycin Oxime + Spinosad (69).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 499
Cattle 203
Cat 175
Pig 27
Human 13
Horse 13
Chicken 3
Goat 2
Other 2
Fish 1

Breeds Most Affected

Domestic Shorthair 85
Cattle (unknown) 54
Crossbred Bovine/Cattle 53
Retriever - Labrador 40
Crossbred Canine/dog 33
Chihuahua 33
Mixed (Cattle) 26
Domestic (unspecified) 25
Cattle (other) 25
Unknown 21

Associated Drugs

Milbemycin Oxime + Spinosad 69
Monensin Sodium 68
Maropitant Citrate 57
Cefovecin 49
Enrofloxacin 47
Moxidectin 44
Fenbendazole 42
Tylosin Phosphate 39
Oclacitinib Maleate 39
Spinosad 36
Dexmedetomidine Hydrochloride 32
Dexamethasone 30
Ractopamine Hydrochloride 29
Prednisone 29
Carprofen 28
Tulathromycin 26
Selamectin 25
Trenbolone; Estradiol; Tylosin Tartrate 25
Isoflurane 25
Doxycycline 23

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Respiratory tract disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (48.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Respiratory tract disorder NOS (#409 of 2,481 by report volume); death-coded 48.7%. PlainBreed reaction plate · death-coded report count stamp 460 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →