NT - chronic (interstitial) pneumonia/pleuropneumonia

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VeDDRA Code: 2297

17 adverse event reports referencing this reaction

17
Total Reports
14
Deaths
8240.0%
Death Rate

Species Most Affected

Cattle 9
Dog 6
Pig 1
Cat 1

Breeds Most Affected

Jersey 2
Holstein-Friesian also known as Holstein 2
Cattle (other) 2
Mixed (Dog) 1
Siberian Husky 1
Terrier (unspecified) 1
Cattle (unknown) 1
Hound - Basset 1
Beefmaster 1
Shepherd Dog - German 1

Associated Drugs

Tulathromycin 3
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 3
Ceftiofur Crystalline Free Acid 2
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 2
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 2
Ivermectin + Pyrantel As Pamoate Salt 2
Mannheimia Haemolytica, Strain Nl-1009 1
Clostridium Perfringens Type C, Pc8, Kb; Clostridium Perfringens Type D, 317, Kb 1
Ceftiofur Hydrochloride 1
Doramectin; Phenol 1
Ivermectin 272Mcg, Pyrantel 227Mg 1
Danofloxacin Mesylate 1
Lufenuron + Milbemycin Oxime 1
Milbemcyin Oxime, Lufenuron, Praziquantel 1
Milbemycin Oxime, Lufenuron 1
Tilmicosin Phosphate 1
Bovine Rhinotracheitis + Virus Diarrhea + Parainfluenza 3 + Respiratory Syncytial Virus Vaccine 1
Haemophilus Somnus Vaccine 1
Mycoplasma Vaccine 1
Melarsomine Dihydrochloride Injection 1

Data Summary

Metric Value
Total reports referencing reaction 17
Reports with fatal outcome 14
Case-fatality rate (reported events) 8240.0%
Species observed 4
Breeds observed 14
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2297.

NT - chronic (interstitial) pneumonia/pleuropneumonia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 17 adverse event reports that reference NT - chronic (interstitial) pneumonia/pleuropneumonia as a reaction term, including 14 reports with a death outcome — a 8240.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2297, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

NT - chronic (interstitial) pneumonia/pleuropneumonia appears most frequently in reports for Cattle (9 reports), Dog (6 reports), Pig (1 reports) — with Cattle dominating at 9 entries. Within those species, the breeds most often named alongside this reaction are Jersey (2), Holstein-Friesian also known as Holstein (2), Cattle (other) (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with NT - chronic (interstitial) pneumonia/pleuropneumonia are Tulathromycin (3 reports), Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn (3 reports), Ceftiofur Crystalline Free Acid (2 reports), Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt (2 reports), with Tulathromycin appearing alongside this reaction in 3 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial