Reaction profile

The FDA adverse-event record for polycythaemia

397 FDA reports name polycythaemia, a high-volume reaction in the CVM extract (VeDDRA 2521). Plate stamps and neighbourhood peers follow.

#731 of 2,481
by report volume (all reactions)
397
reports citing this reaction
23.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Polycythaemia has 397 reports now versus 397 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Polycythaemia changes

FDA AER · VeDDRA plate

Code 2521 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 397 reports
  • DEATH-HOT 23.4%
  • MID-PACK #731/2481
  • PHOTO-FINISH Elevated protein:crea…
  • SPECIES-DOG Dog · 345
  • DRUG-LEAD Carprofen · 59
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Elevated protein:creatinine ratio (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Polycythaemia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348INEFFECTIVE, OTHER DR… · near398Elevated protein:crea… · near397Polycythaemia · this reaction397Corneal disorder NOS · near396Hearing decreased · near396Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Polycythaemia

What the FDA AER plate says about Polycythaemia

Signature read: 93 death-coded reports is a heavy tail count for Polycythaemia in the CVM extract. Report volume is upper-third scale: 397 named reports in the openFDA extract. 93 of 397 reports were death-coded (23.4% of named reports, not a population mortality rate). Nearest volume peer: Elevated protein:creatinine ratio (±0 reports). Lead species Dog (345). Lead co-reported drug Carprofen (59).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 345
Cat 46
Horse 6

Breeds Most Affected

Retriever - Labrador 59
Crossbred Canine/dog 40
Domestic Shorthair 20
Shepherd Dog - German 18
Terrier - Yorkshire 16
Dachshund (unspecified) 13
Retriever - Golden 12
Terrier - Boston 8
Shih Tzu 8
Domestic (unspecified) 8

Associated Drugs

Carprofen 59
Maropitant Citrate 30
Meloxicam 26
Deracoxib 22
Spinosad 19
Milbemycin Oxime + Spinosad 17
Grapiprant 16
Afoxolaner 15
Oclacitinib Maleate 14
Moxidectin 13
Milbemycin Oxime + Praziquantel 13
Maropitant 12
Famotidine 12
Melarsomine Dihydrochloride Injection 11
Fluralaner Chew Tablets 11
Metronidazole 10
Lotilaner 10
Dexamethasone 9
Gabapentin 9
Bedinvetmab 9

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Polycythaemia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (23.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Polycythaemia (#731 of 2,481 by report volume); death-coded 23.4%. PlainBreed reaction plate · death-coded report count stamp 93 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →