Reaction profile

The FDA adverse-event record for localised hair loss

1,712 FDA reports name localised hair loss, a high-volume reaction in the CVM extract (VeDDRA 1581). Plate stamps and neighbourhood peers follow.

#260 of 2,481
by report volume (all reactions)
1,712
reports citing this reaction
2.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Localised hair loss has 1,712 reports now versus 1,676 in that prior snapshot: 36 more (2.1%).

Report change
+36
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Localised hair loss changes

FDA AER · VeDDRA plate

Code 1581 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,712 reports
  • DEATH-LOW 2.8%
  • UPPER-Q #260/2481
  • PHOTO-FINISH Loss of hearing
  • SPECIES-DOG Dog · 950
  • DRUG-LEAD Frunevetmab · 195
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Loss of hearing (±5 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Localised hair loss

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Uncomfortable · near1733Localised hair loss · this r…1712Loss of hearing · near1707Unresponsive to stimu… · near1696Application site lesi… · near1693Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Localised hair loss

Localised hair loss: low death-coded share in the FDA AER plate

Signature read: 1,712 reports place Localised hair loss in the upper third of FDA AER volume (#260 of 2,481). Report volume is upper-third scale: 1,712 named reports in the openFDA extract. Death-coded share is lower-third: 48 of 1,712 reports (2.8% of named reports). Nearest volume peer: Loss of hearing (±5 reports). Lead species Dog (950). Lead co-reported drug Frunevetmab (195).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Frunevetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 950
Cat 631
Cattle 90
Horse 29
Human 5
Ferret 3
Llama 1
Other 1
Other Mammals 1
Other Canids 1

Breeds Most Affected

Domestic Shorthair 404
Retriever - Labrador 117
Shepherd Dog - German 65
Crossbred Canine/dog 65
Chihuahua 52
Domestic Longhair 50
Domestic Mediumhair 41
Retriever - Golden 36
Cat (unknown) 33
Cat (other) 31

Associated Drugs

Frunevetmab 195
Milbemycin Oxime + Spinosad 156
Afoxolaner 112
Selamectin 96
Fluralaner Spot-On Solution 86
Selamectin;Sarolaner 73
Oclacitinib Maleate 71
Fluralaner Chew Tablets 71
Trilostane 69
Spinosad 52
Fluralaner 13.64% 12-Week Chew 49
Fluralaner/Moxidectin Spot-On 48
Cefovecin 47
Ivermectin + Pyrantel As Pamoate Salt 46
Prednisone 44
Pyrantel Pamoate;Sarolaner 43
Bedinvetmab 42
Imidacloprid + Moxidectin 41
Gabapentin 38
Ivermectin 33

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Localised hair loss, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,712 here).

Similar death-coded share

Nearest other reactions by death-coded share (2.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Localised hair loss (#260 of 2,481 by report volume); death-coded 2.8%. PlainBreed reaction plate · report volume stamp 1,712 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →