Reaction profile

The FDA adverse-event record for localised hair loss

1,624 FDA adverse-event reports reference localised hair loss (VeDDRA 1581). See the species, breeds, and drugs most associated with it below.

1,624
reports citing this reaction
2.8%
death-coded share
Dog
most-affected species
Frunevetmab
most-associated drug
Verify with FDA CVM →
1,624
Total Reports
46
Deaths
2.8%
Death Rate

Species Most Affected

Dog 908
Cat 586
Cattle 90
Horse 28
Human 5
Ferret 3
Llama 1
Other 1
Other Mammals 1
Other Canids 1

Breeds Most Affected

Domestic Shorthair 373
Retriever - Labrador 112
Shepherd Dog - German 64
Crossbred Canine/dog 59
Chihuahua 49
Domestic Longhair 46
Domestic Mediumhair 41
Retriever - Golden 33
Cat (unknown) 31
Cat (other) 29

Associated Drugs

Frunevetmab 171
Milbemycin Oxime + Spinosad 156
Afoxolaner 108
Selamectin 94
Fluralaner Spot-On Solution 82
Fluralaner Chew Tablets 71
Trilostane 68
Selamectin;Sarolaner 67
Oclacitinib Maleate 66
Spinosad 52
Ivermectin + Pyrantel As Pamoate Salt 46
Cefovecin 46
Fluralaner 13.64% 12-Week Chew 44
Fluralaner/Moxidectin Spot-On 44
Imidacloprid + Moxidectin 41
Pyrantel Pamoate;Sarolaner 41
Prednisone 38
Bedinvetmab 35
Ivermectin 33
Gabapentin 32

Localised hair loss Reaction Insights

1,624 reports name Localised hair loss; 46 recorded a death outcome (2.8% of reported events, not a population-level mortality rate). VeDDRA code: 1581.

By species: Dog (908 reports), Cat (586 reports), Cattle (90 reports). By breed: Domestic Shorthair (373), Retriever - Labrador (112), Shepherd Dog - German (64).

Most co-reported drugs: Frunevetmab (171 reports), Milbemycin Oxime + Spinosad (156 reports), Afoxolaner (108 reports), Selamectin (94 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.