Reaction profile

The FDA adverse-event record for intestinal haemorrhage

52 FDA adverse-event reports reference intestinal haemorrhage (VeDDRA 1083). See the species, breeds, and drugs most associated with it below.

52
reports citing this reaction
76.9%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
52
Total Reports
40
Deaths
76.9%
Death Rate

Species Most Affected

Dog 44
Cat 4
Pig 2
Other Birds 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 3
Unknown 2
Pig (unknown) 2
Dachshund (unspecified) 2
Shih Tzu 2
Bulldog 2
Terrier - Bull - American Pit 2
Poodle - Miniature 2
Maltese 2
Crossbred Canine/dog 2

Associated Drugs

Carprofen 8
Meloxicam 7
Grapiprant 5
Spinosad 4
Maropitant Citrate 4
Fluralaner Chew Tablets 4
Sucralfate 4
Firocoxib 227 Mg Chewable 3
Milbemycin Oxime + Spinosad 3
Clindamycin 3
Metronidazole 3
Polysulfated Glycosaminoglycan 2
Afoxolaner 2
Cefovecin 2
Deracoxib 2
Gabapentin 2
Buprenorphine 2
Omeprazole 2
Probiotic (Unknown) 2
Rabies Vaccine 2

Intestinal haemorrhage Reaction Insights

52 reports name Intestinal haemorrhage; 40 recorded a death outcome (76.9% of reported events, not a population-level mortality rate). VeDDRA code: 1083.

By species: Dog (44 reports), Cat (4 reports), Pig (2 reports). By breed: Domestic Shorthair (3), Unknown (2), Pig (unknown) (2).

Most co-reported drugs: Carprofen (8 reports), Meloxicam (7 reports), Grapiprant (5 reports), Spinosad (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.