Reaction profile

The FDA adverse-event record for chest tightness

Name: Chest tightness - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

45 FDA reports name chest tightness, a lower-volume reaction in the CVM extract (VeDDRA 1376). Plate stamps and neighbourhood peers follow.

#1793 of 2,481
by report volume (all reactions): 45
reports citing this reaction: 0.0%
death-coded share: Human
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chest tightness has 45 reports now versus 45 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chest tightness changes

FDA AER · VeDDRA plate

Code 1376 VOL-TRACE

VOL-TRACE · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-HUMAN · DRUG-LEAD · DESK-NARROW · BOOK-FULL

VOL-TRACE 45 reports
DEATH-RARE 0.0%
MID-PACK #1793/2481
PHOTO-FINISH Application site disc…
SPECIES-HUMAN Human · 45
DRUG-LEAD Tilmicosin Phosph… · 7
DESK-NARROW 1 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Application site discharge NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Chest tightness

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Chest tightness

Chest tightness: low death-coded share in the FDA AER plate

Signature read: Chest tightness's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 45 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 45 reports (0.0% of named reports). Nearest volume peer: Application site discharge NOS (±0 reports). Lead species Human (45). Lead co-reported drug Tilmicosin Phosphate (7).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Tilmicosin Phosphate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Human 45

Breeds Most Affected

Unknown 45

Associated Drugs

Tilmicosin Phosphate 7

Selamectin 5

Tilmicosin 5

Dinoprost Tromethamine 4

Milbemycin Oxime + Spinosad 2

Ophytrium 2

Maropitant Citrate 2

Nitenpyram 1

Cetirizine 1

Paroxetine 1

Ciprofloxacin 1

Bupropion 1

Imidacloprid + Moxidectin 1

Trilostane 1

Atenolol 1

Losartan 1

Remerol 1

Welcol 1

Hydrocodone 1

Eprinomectin 0.5% Pour-On 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chest tightness (#1793 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →