Reaction profile

The FDA adverse-event record for behavioural disorder nos

24,337 FDA reports name behavioural disorder nos, a high-volume reaction in the CVM extract (VeDDRA 116). Plate stamps and neighbourhood peers follow.

#14 of 2,481
by report volume (all reactions)
24,337
reports citing this reaction
8.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Behavioural disorder NOS has 24,337 reports now versus 24,031 in that prior snapshot: 306 more (1.3%).

Report change
+306
Death-coded reports
+23
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Behavioural disorder NOS changes

FDA AER · VeDDRA plate

Code 116 VOL-HIGH

VOL-HIGH · DEATH-PAR · TOP-DECILE · NEAR-PEER · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-HIGH 24,337 reports
  • DEATH-PAR 8.3%
  • TOP-DECILE #14/2481
  • NEAR-PEER Digestive tract disor…
  • SPECIES-DOG Dog · 17,388
  • DRUG-LEAD Milbemycin Oxime… · 4,115
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Digestive tract disorder NOS (±1,589 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Behavioural disorder NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348UNPALATABLE · near27321Behavioural disorder… · this…24337Digestive tract disor… · near22748Ataxia · near21626Other abnormal test r… · near21162Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Behavioural disorder NOS

What the FDA AER plate says about Behavioural disorder NOS

Signature read: 24,337 reports place Behavioural disorder NOS in the upper third of FDA AER volume (#14 of 2,481). Report volume is upper-third scale: 24,337 named reports in the openFDA extract. 2,025 of 24,337 reports were death-coded (8.3% of named reports, not a population mortality rate). Nearest volume peer: Digestive tract disorder NOS (±1,589 reports). Lead species Dog (17,388). Lead co-reported drug Milbemycin Oxime + Spinosad (4,115).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 17,388
Cat 6,255
Horse 379
Cattle 212
Pig 24
Turkey 13
Rabbit 10
Chicken 9
Other 6
Sheep 5

Breeds Most Affected

Domestic Shorthair 3,407
Retriever - Labrador 1,546
Crossbred Canine/dog 1,313
Chihuahua 973
Terrier - Yorkshire 782
Cat (unknown) 729
Dog (unknown) 716
Retriever - Golden 678
Shih Tzu 663
Domestic Longhair 566

Associated Drugs

Milbemycin Oxime + Spinosad 4,115
Imidacloprid + Moxidectin 1,776
Spinosad 1,366
Afoxolaner 1,262
Buprenorphine 1,069
Selamectin 957
Ivermectin + Pyrantel As Pamoate Salt 767
Oclacitinib Maleate 756
Milbemycin Oxime + Praziquantel 750
Fluralaner Chew Tablets 700
Carprofen 686
Maropitant Citrate 671
Nitenpyram 659
Pyrantel Pamoate;Sarolaner 654
Lotilaner 531
Sarolaner 521
Trilostane 517
Gabapentin 461
Bedinvetmab 461
Fluralaner Spot-On Solution 441

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Behavioural disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (24,337 here).

Similar death-coded share

Nearest other reactions by death-coded share (8.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Behavioural disorder NOS (#14 of 2,481 by report volume); death-coded 8.3%. PlainBreed reaction plate · report volume stamp 24,337 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →