Reaction profile

The FDA adverse-event record for glazed eye

1,333 FDA reports name glazed eye, a high-volume reaction in the CVM extract (VeDDRA 1211). Plate stamps and neighbourhood peers follow.

#313 of 2,481
by report volume (all reactions)
1,333
reports citing this reaction
8.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Glazed eye has 1,333 reports now versus 1,320 in that prior snapshot: 13 more (1.0%).

Report change
+13
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Glazed eye changes

FDA AER · VeDDRA plate

Code 1211 VOL-MID

VOL-MID · DEATH-PAR · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,333 reports
  • DEATH-PAR 8.8%
  • UPPER-Q #313/2481
  • PHOTO-FINISH Underfilling, Bottles
  • SPECIES-DOG Dog · 1,170
  • DRUG-LEAD Milbemycin Oxime… · 372
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Underfilling, Bottles (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Glazed eye

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Alopecia NOS · near1335Liver disorder NOS · near1335INEFFECTIVE, COCCIDIA · near1334Glazed eye · this reaction1333Underfilling, Bottles · near1333Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Glazed eye

What the FDA AER plate says about Glazed eye

Signature read: 1,333 reports place Glazed eye in the upper third of FDA AER volume (#313 of 2,481). Report volume is upper-third scale: 1,333 named reports in the openFDA extract. 117 of 1,333 reports were death-coded (8.8% of named reports, not a population mortality rate). Nearest volume peer: Underfilling, Bottles (±0 reports). Lead species Dog (1,170). Lead co-reported drug Milbemycin Oxime + Spinosad (372).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,170
Cat 154
Horse 3
Rabbit 1
Other Birds 1
Cattle 1
Chicken 1
Hamster 1
Goat 1

Breeds Most Affected

Crossbred Canine/dog 87
Retriever - Labrador 81
Domestic Shorthair 73
Chihuahua 67
Terrier - Yorkshire 56
Maltese 51
Boxer (German Boxer) 50
Shih Tzu 43
Retriever - Golden 41
Shepherd Dog - German 34

Associated Drugs

Milbemycin Oxime + Spinosad 372
Afoxolaner 122
Spinosad 114
Ivermectin + Pyrantel As Pamoate Salt 73
Pyrantel Pamoate;Sarolaner 55
Fluralaner Chew Tablets 46
Imidacloprid + Moxidectin 38
Milbemycin Oxime + Praziquantel 36
Carprofen 35
Fluralaner 13.64% 12-Week Chew 31
Selamectin 30
Trilostane 30
Bedinvetmab 30
Lotilaner 26
Sarolaner 23
Ivermectin 22
Spinosad, Milbemycin 22
Prednisone 20
Moxidectin 20
Buprenorphine 20

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Glazed eye, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,333 here).

Similar death-coded share

Nearest other reactions by death-coded share (8.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Glazed eye (#313 of 2,481 by report volume); death-coded 8.8%. PlainBreed reaction plate · report volume stamp 1,333 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →