Precipitate, Sediment

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VeDDRA Code: 99962

1,221 adverse event reports referencing this reaction

1,221
Total Reports
6
Deaths
50.0%
Death Rate

Species Most Affected

Unknown 1,152
Dog 45
Cat 13
Cattle 4
Horse 3
Human 1
Other 1
Sheep 1
Rat 1

Breeds Most Affected

Unknown 1,154
Crossbred Canine/dog 11
Domestic Shorthair 7
Chihuahua 6
Dog (unknown) 5
Cat (other) 4
Bichon Frise 3
Terrier (unspecified) 3
Terrier - Jack Russell 3
Cattle (other) 2

Associated Drugs

Cefovecin 146
Insulin Injectable Vial 136
Moxidectin 124
Enrofloxacin 120
Ceftiofur Sodium 108
Maropitant Citrate 80
Selamectin 72
Furosemide Injection 65
Triamcinolone Acetonide 40
Selamectin;Sarolaner 33
Protamine Zinc Recombinant Human Insulin 19
Doramectin 18
Dexmedetomidine Hydrochloride 17
Propofol 17
Methylprednisolone Acetate 16
Doramectin; Phenol 11
Ceftiofur Hydrochloride 11
Tulathromycin 11
Butorphanol Injectable 10
Tiletamine Hcl;Zolazapam Hcl 10

Data Summary

Metric Value
Total reports referencing reaction 1,221
Reports with fatal outcome 6
Case-fatality rate (reported events) 50.0%
Species observed 9
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99962.

Precipitate, Sediment Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,221 adverse event reports that reference Precipitate, Sediment as a reaction term, including 6 reports with a death outcome — a 50.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99962, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Precipitate, Sediment appears most frequently in reports for Unknown (1,152 reports), Dog (45 reports), Cat (13 reports) — with Unknown dominating at 1,152 entries. Within those species, the breeds most often named alongside this reaction are Unknown (1,154), Crossbred Canine/dog (11), Domestic Shorthair (7). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Precipitate, Sediment are Cefovecin (146 reports), Insulin Injectable Vial (136 reports), Moxidectin (124 reports), Enrofloxacin (120 reports), with Cefovecin appearing alongside this reaction in 146 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial