Reaction profile

The FDA adverse-event record for ineffective, weight inc

85 FDA adverse-event reports reference ineffective, weight inc (VeDDRA 99157). See the species, breeds, and drugs most associated with it below.

85
reports citing this reaction
27.1%
death-coded share
Cattle
most-affected species
Progesterone;Estradiol Benzoate
most-associated drug
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85
Total Reports
23
Deaths
27.1%
Death Rate

Species Most Affected

Cattle 71
Pig 8
Cat 3
Chicken 2
Dog 1

Breeds Most Affected

Mixed (Cattle) 17
Holstein-Friesian also known as Holstein 15
Crossbred Bovine/Cattle 11
Cattle (unknown) 8
Aberdeen Angus 5
Pig (unknown) 5
Cattle (other) 5
Charolais 4
Pig (other) 3
Domestic Shorthair 3

Associated Drugs

Progesterone;Estradiol Benzoate 16
Trenbolone Acet/Estradiol Impl 11
Ractopamine Hydrochloride 9
Estradiol 8
Estradiol, Trenbolone Acetate 5
Trenbolone Acet/Estrad Sr Imp 5
Zilpaterol 4
Monensin Sodium 4
Ibr/Brsv/P13/Bvd T1, T2(Us) Lv 4
Ivermectin 3
Bovine Virus*5/Past M+Mh Lv/Lb 3
Ibr / Pi3 (Orig S-P Us) Lv 3
Clostr Perf*2/Clos Others*4 Kb 3
Mirtazapine 3
Eprinomectin 2
Monensin 2
Doramectin 2
Estradiol + Trenbolone 2
Fenbendazole 2
Fenbendazol Suspension 2

INEFFECTIVE, WEIGHT INC Reaction Insights

85 reports name INEFFECTIVE, WEIGHT INC; 23 recorded a death outcome (27.1% of reported events, not a population-level mortality rate). VeDDRA code: 99157.

By species: Cattle (71 reports), Pig (8 reports), Cat (3 reports). By breed: Mixed (Cattle) (17), Holstein-Friesian also known as Holstein (15), Crossbred Bovine/Cattle (11).

Most co-reported drugs: Progesterone;Estradiol Benzoate (16 reports), Trenbolone Acet/Estradiol Impl (11 reports), Ractopamine Hydrochloride (9 reports), Estradiol (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.