Reaction profile

The FDA adverse-event record for dermal mass

1,070 FDA adverse-event reports reference dermal mass (VeDDRA 2262). See the species, breeds, and drugs most associated with it below.

1,070
reports citing this reaction
8.3%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
1,070
Total Reports
89
Deaths
8.3%
Death Rate

Species Most Affected

Dog 1,035
Cat 32
Horse 2
Human 1

Breeds Most Affected

Retriever - Labrador 133
Crossbred Canine/dog 70
Terrier - Bull - American Pit 63
Retriever - Golden 56
Boxer (German Boxer) 55
Dog (unknown) 33
Shih Tzu 29
Beagle 29
Shepherd Dog - German 28
Pug 22

Associated Drugs

Oclacitinib Maleate 575
Cyclosporine 78
Milbemycin Oxime + Spinosad 70
Trilostane 62
Anti-Il31 Mab Mcs Lot #1283563 55
Carprofen 47
Bedinvetmab 42
Prednisone 40
Afoxolaner 34
Milbemycin Oxime + Praziquantel 31
Gabapentin 28
Fluralaner Chew Tablets 26
Cephalexin 26
Cefpodoxime Proxetil 24
Moxidectin 24
Ivermectin + Pyrantel As Pamoate Salt 20
Selamectin 19
Tramadol 19
Prednisolone; Trimeprazine Tartrate 17
Cefovecin 15

Dermal mass Reaction Insights

1,070 reports name Dermal mass; 89 recorded a death outcome (8.3% of reported events, not a population-level mortality rate). VeDDRA code: 2262.

By species: Dog (1,035 reports), Cat (32 reports), Horse (2 reports). By breed: Retriever - Labrador (133), Crossbred Canine/dog (70), Terrier - Bull - American Pit (63).

Most co-reported drugs: Oclacitinib Maleate (575 reports), Cyclosporine (78 reports), Milbemycin Oxime + Spinosad (70 reports), Trilostane (62 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.