Reaction profile

The FDA adverse-event record for dermal mass

1,109 FDA reports name dermal mass, a high-volume reaction in the CVM extract (VeDDRA 2262). Plate stamps and neighbourhood peers follow.

#365 of 2,481
by report volume (all reactions)
1,109
reports citing this reaction
8.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Dermal mass has 1,109 reports now versus 1,093 in that prior snapshot: 16 more (1.5%).

Report change
+16
Death-coded reports
+2
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Dermal mass changes

FDA AER · VeDDRA plate

Code 2262 VOL-MID

VOL-MID · DEATH-PAR · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,109 reports
  • DEATH-PAR 8.3%
  • UPPER-Q #365/2481
  • PHOTO-FINISH Application site scra…
  • SPECIES-DOG Dog · 1,072
  • DRUG-LEAD Oclacitinib Malea… · 598
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site scratching (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Dermal mass

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Sleepiness - neurolog… · near1112Balance problem · near1111Application site scra… · near1110Dermal mass · this reaction1109Faecal incontinence · near1107Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Dermal mass

What the FDA AER plate says about Dermal mass

Signature read: 1,109 reports place Dermal mass in the upper third of FDA AER volume (#365 of 2,481). Report volume is upper-third scale: 1,109 named reports in the openFDA extract. 92 of 1,109 reports were death-coded (8.3% of named reports, not a population mortality rate). Nearest volume peer: Application site scratching (±1 reports). Lead species Dog (1,072). Lead co-reported drug Oclacitinib Maleate (598).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,072
Cat 34
Horse 2
Human 1

Breeds Most Affected

Retriever - Labrador 136
Crossbred Canine/dog 70
Terrier - Bull - American Pit 66
Retriever - Golden 61
Boxer (German Boxer) 55
Dog (unknown) 34
Shih Tzu 30
Beagle 29
Shepherd Dog - German 28
Pug 24

Associated Drugs

Oclacitinib Maleate 598
Cyclosporine 79
Milbemycin Oxime + Spinosad 70
Trilostane 64
Anti-Il31 Mab Mcs Lot #1283563 57
Bedinvetmab 52
Carprofen 51
Prednisone 43
Afoxolaner 36
Milbemycin Oxime + Praziquantel 32
Gabapentin 30
Fluralaner Chew Tablets 26
Cephalexin 26
Cefpodoxime Proxetil 24
Moxidectin 24
Tramadol 22
Ivermectin + Pyrantel As Pamoate Salt 20
Selamectin 19
Fluralaner 19
Prednisolone; Trimeprazine Tartrate 17

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Dermal mass, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (8.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Dermal mass (#365 of 2,481 by report volume); death-coded 8.3%. PlainBreed reaction plate · report volume stamp 1,109 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →