Reaction profile

The FDA adverse-event record for electrolyte disorder

1,105 FDA reports name electrolyte disorder, a high-volume reaction in the CVM extract (VeDDRA 2144). Plate stamps and neighbourhood peers follow.

#367 of 2,481
by report volume (all reactions)
1,105
reports citing this reaction
23.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Electrolyte disorder has 1,105 reports now versus 1,095 in that prior snapshot: 10 more (0.9%).

Report change
+10
Death-coded reports
+1
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Electrolyte disorder changes

FDA AER · VeDDRA plate

Code 2144 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,105 reports
  • DEATH-HOT 23.9%
  • UPPER-Q #367/2481
  • PHOTO-FINISH Faecal incontinence
  • SPECIES-DOG Dog · 965
  • DRUG-LEAD Trilostane · 611
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Faecal incontinence (±2 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Electrolyte disorder

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site scra… · near1110Dermal mass · near1109Faecal incontinence · near1107Electrolyte disorder · this …1105Flaking skin · near1102Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Electrolyte disorder

What the FDA AER plate says about Electrolyte disorder

Signature read: 264 death-coded reports is a heavy tail count for Electrolyte disorder in the CVM extract. Report volume is upper-third scale: 1,105 named reports in the openFDA extract. 264 of 1,105 reports were death-coded (23.9% of named reports, not a population mortality rate). Nearest volume peer: Faecal incontinence (±2 reports). Lead species Dog (965). Lead co-reported drug Trilostane (611).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 965
Cat 126
Horse 14

Breeds Most Affected

Retriever - Labrador 82
Domestic Shorthair 78
Chihuahua 49
Crossbred Canine/dog 47
Terrier - Yorkshire 42
Maltese 39
Terrier - Boston 34
Shih Tzu 32
Beagle 27
Dachshund - Miniature 26

Associated Drugs

Trilostane 611
Milbemycin Oxime + Spinosad 134
Maropitant Citrate 69
Prednisone 53
Spinosad 52
Carprofen 48
Meloxicam 37
Desoxycortone 31
Desoxycorticosterone Pivalate 30
Oclacitinib Maleate 30
Gabapentin 27
Bedinvetmab 25
Tramadol 24
Insulin 23
Cefovecin 22
Furosemide 19
Buprenorphine 19
Deracoxib 19
Famotidine 17
Afoxolaner 17

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Electrolyte disorder, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,105 here).

Similar death-coded share

Nearest other reactions by death-coded share (23.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Electrolyte disorder (#367 of 2,481 by report volume); death-coded 23.9%. PlainBreed reaction plate · death-coded report count stamp 264 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →