Reaction profile

The FDA adverse-event record for palpable mass nos

609 FDA reports name palpable mass nos, a high-volume reaction in the CVM extract (VeDDRA 2000). Plate stamps and neighbourhood peers follow.

#569 of 2,481
by report volume (all reactions)
609
reports citing this reaction
23.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Palpable mass NOS has 609 reports now versus 605 in that prior snapshot: 4 more (0.7%).

Report change
+4
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Palpable mass NOS changes

FDA AER · VeDDRA plate

Code 2000 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 609 reports
  • DEATH-HOT 23.0%
  • UPPER-Q #569/2481
  • PHOTO-FINISH Colitis
  • SPECIES-DOG Dog · 560
  • DRUG-LEAD Milbemycin Oxime… · 154
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Colitis (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Palpable mass NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Found dead · near610Periorbital oedema · near610Palpable mass NOS · this rea…609Colitis · near608Lack of efficacy (pro… · near606Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Palpable mass NOS

What the FDA AER plate says about Palpable mass NOS

Signature read: 140 death-coded reports is a heavy tail count for Palpable mass NOS in the CVM extract. Report volume is upper-third scale: 609 named reports in the openFDA extract. 140 of 609 reports were death-coded (23.0% of named reports, not a population mortality rate). Nearest volume peer: Colitis (±1 reports). Lead species Dog (560). Lead co-reported drug Milbemycin Oxime + Spinosad (154).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 560
Cat 46
Horse 3

Breeds Most Affected

Retriever - Labrador 79
Domestic Shorthair 33
Retriever - Golden 29
Boxer (German Boxer) 27
Crossbred Canine/dog 26
Shepherd Dog - German 26
Beagle 18
Chihuahua 17
Terrier - Bull - American Pit 17
Dog (unknown) 15

Associated Drugs

Milbemycin Oxime + Spinosad 154
Oclacitinib Maleate 125
Carprofen 37
Trilostane 36
Milbemycin Oxime + Praziquantel 29
Spinosad 27
Maropitant Citrate 25
Milbemycin Oxime 24
Tramadol 20
Meloxicam 20
Anti-Il31 Mab Mcs Lot #1283563 19
Enrofloxacin 18
Imidacloprid + Moxidectin 17
Ivermectin 16
Gabapentin 15
Moxidectin 15
Afoxolaner 15
Grapiprant 15
Cefovecin 14
Prednisone 13

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Palpable mass NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (609 here).

Similar death-coded share

Nearest other reactions by death-coded share (23.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Palpable mass NOS (#569 of 2,481 by report volume); death-coded 23.0%. PlainBreed reaction plate · death-coded report count stamp 140 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →