Reaction profile

The FDA adverse-event record for nystagmus

2,489 FDA reports name nystagmus, a high-volume reaction in the CVM extract (VeDDRA 691). Plate stamps and neighbourhood peers follow.

#192 of 2,481
by report volume (all reactions)
2,489
reports citing this reaction
16.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Nystagmus has 2,489 reports now versus 2,453 in that prior snapshot: 36 more (1.5%).

Report change
+36
Death-coded reports
+6
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Nystagmus changes

FDA AER · VeDDRA plate

Code 691 VOL-MID

VOL-MID · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,489 reports
  • DEATH-ELEV 16.4%
  • TOP-DECILE #192/2481
  • PHOTO-FINISH Head tremor
  • SPECIES-DOG Dog · 1,929
  • DRUG-LEAD Florfenicol + Mom… · 289
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Head tremor (±4 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Nystagmus

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Licking · near2506Vials, Damaged · near2500Elevated aspartate am… · near2499Nystagmus · this reaction2489Head tremor · near2485Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Nystagmus

What the FDA AER plate says about Nystagmus

Signature read: 409 death-coded reports is a heavy tail count for Nystagmus in the CVM extract. Report volume is upper-third scale: 2,489 named reports in the openFDA extract. 409 of 2,489 reports were death-coded (16.4% of named reports, not a population mortality rate). Nearest volume peer: Head tremor (±4 reports). Lead species Dog (1,929). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (289).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,929
Cat 489
Horse 45
Cattle 14
Rabbit 4
Sheep 2
Other Deer 1
Ferret 1
Pig 1
Monkey 1

Breeds Most Affected

Domestic Shorthair 289
Retriever - Labrador 207
Crossbred Canine/dog 162
Retriever - Golden 95
Shih Tzu 74
Chihuahua 68
Shepherd Dog - German 61
Shepherd Dog - Australian 58
Collie - Border 55
Boxer (German Boxer) 54

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 289
Bedinvetmab 274
Maropitant Citrate 214
Carprofen 147
Milbemycin Oxime + Spinosad 123
Gabapentin 118
Afoxolaner 113
Pyrantel Pamoate;Sarolaner 84
Selamectin 77
Prednisone 73
Fluralaner Chew Tablets 71
Spinosad 68
Sarolaner 63
Cefovecin 60
Moxidectin 59
Propofol 57
Oclacitinib Maleate 57
Enrofloxacin 53
Isoflurane 53
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 50

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Nystagmus, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,489 here).

Similar death-coded share

Nearest other reactions by death-coded share (16.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Nystagmus (#192 of 2,481 by report volume); death-coded 16.4%. PlainBreed reaction plate · death-coded report count stamp 409 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →