Reaction profile

The FDA adverse-event record for pallor

550 FDA reports name pallor, a high-volume reaction in the CVM extract (VeDDRA 1215). Plate stamps and neighbourhood peers follow.

#608 of 2,481
by report volume (all reactions)
550
reports citing this reaction
33.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pallor has 550 reports now versus 547 in that prior snapshot: 3 more (0.5%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pallor changes

FDA AER · VeDDRA plate

Code 1215 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 550 reports
  • DEATH-HOT 33.6%
  • UPPER-Q #608/2481
  • PHOTO-FINISH Fly biting behaviour
  • SPECIES-DOG Dog · 460
  • DRUG-LEAD Moxidectin · 130
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Fly biting behaviour (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Pallor

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Gastric ulcer · near551Fly biting behaviour · near550Increased borborygmus · near550Pallor · this reaction550Unexplained death · near550Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pallor

Pallor: high death-coded share in the FDA AER plate

Signature read: 185 death-coded reports is a heavy tail count for Pallor in the CVM extract. Report volume is upper-third scale: 550 named reports in the openFDA extract. Death-coded share is upper-third: 185 of 550 reports (33.6% of named reports). Nearest volume peer: Fly biting behaviour (±0 reports). Lead species Dog (460). Lead co-reported drug Moxidectin (130).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 460
Cat 69
Horse 9
Pig 3
Human 3
Sheep 2
Chicken 2
Goat 1
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 39
Domestic Shorthair 36
Retriever - Labrador 33
Terrier - Yorkshire 24
Chihuahua 23
Shih Tzu 21
Boxer (German Boxer) 21
Shepherd Dog - German 19
Pug 16
Maltese 14

Associated Drugs

Moxidectin 130
Milbemycin Oxime + Spinosad 47
Carprofen 40
Maropitant Citrate 38
Melarsomine Dihydrochloride 27
Cefovecin 23
Spinosad 19
Prednisone 19
Diphenhydramine Hcl 18
Selamectin 16
Meloxicam 15
Milbemycin Oxime + Praziquantel 15
Rabies Virus, 15
Oclacitinib Maleate 14
Pyrantel Pamoate 13
Dexamethasone 13
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 13
Butorphanol 12
Gabapentin 11
Triamcinolone Acetonide 10

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Pallor, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (550 here).

Similar death-coded share

Nearest other reactions by death-coded share (33.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pallor (#608 of 2,481 by report volume); death-coded 33.6%. PlainBreed reaction plate · death-coded report count stamp 185 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →