Reaction profile

The FDA adverse-event record for pallor

540 FDA adverse-event reports reference pallor (VeDDRA 1215). See the species, breeds, and drugs most associated with it below.

540
reports citing this reaction
33.3%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
540
Total Reports
180
Deaths
33.3%
Death Rate

Species Most Affected

Dog 453
Cat 67
Horse 9
Pig 3
Sheep 2
Human 2
Chicken 2
Goat 1
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 38
Domestic Shorthair 36
Retriever - Labrador 33
Terrier - Yorkshire 23
Chihuahua 23
Shih Tzu 21
Boxer (German Boxer) 21
Shepherd Dog - German 19
Pug 15
Maltese 13

Associated Drugs

Moxidectin 129
Milbemycin Oxime + Spinosad 47
Carprofen 40
Maropitant Citrate 36
Melarsomine Dihydrochloride 27
Cefovecin 23
Spinosad 19
Prednisone 19
Diphenhydramine Hcl 18
Selamectin 15
Meloxicam 15
Milbemycin Oxime + Praziquantel 15
Rabies Virus, 15
Oclacitinib Maleate 14
Pyrantel Pamoate 13
Dexamethasone 13
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 13
Butorphanol 12
Gabapentin 11
Triamcinolone Acetonide 10

Pallor Reaction Insights

540 reports name Pallor; 180 recorded a death outcome (33.3% of reported events, not a population-level mortality rate). VeDDRA code: 1215.

By species: Dog (453 reports), Cat (67 reports), Horse (9 reports). By breed: Crossbred Canine/dog (38), Domestic Shorthair (36), Retriever - Labrador (33).

Most co-reported drugs: Moxidectin (129 reports), Milbemycin Oxime + Spinosad (47 reports), Carprofen (40 reports), Maropitant Citrate (36 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.