Reaction profile

The FDA adverse-event record for ecchymosis

417 FDA adverse-event reports reference ecchymosis (VeDDRA 2038). See the species, breeds, and drugs most associated with it below.

417
reports citing this reaction
33.6%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
417
Total Reports
140
Deaths
33.6%
Death Rate

Species Most Affected

Dog 350
Cat 34
Human 29
Cattle 2
Horse 1
Other Birds 1

Breeds Most Affected

Crossbred Canine/dog 35
Retriever - Labrador 31
Unknown 30
Chihuahua 18
Maltese 17
Retriever - Golden 15
Domestic (unspecified) 13
Poodle (unspecified) 12
Dachshund (unspecified) 12
Pit Bull 10

Associated Drugs

Carprofen 73
Maropitant Citrate 32
Meloxicam 31
Moxidectin 26
Prednisone 23
Doxycycline 20
Milbemycin Oxime + Spinosad 19
Cefovecin 18
Bedinvetmab 16
Deracoxib 15
Cefpodoxime Proxetil 15
Oclacitinib Maleate 15
Cefovecin Sodium 14
Dexamethasone 13
Metronidazole 13
Enrofloxacin 12
Trilostane 11
Famotidine 11
Diphenhydramine 11
Afoxolaner 11

Ecchymosis Reaction Insights

417 reports name Ecchymosis; 140 recorded a death outcome (33.6% of reported events, not a population-level mortality rate). VeDDRA code: 2038.

By species: Dog (350 reports), Cat (34 reports), Human (29 reports). By breed: Crossbred Canine/dog (35), Retriever - Labrador (31), Unknown (30).

Most co-reported drugs: Carprofen (73 reports), Maropitant Citrate (32 reports), Meloxicam (31 reports), Moxidectin (26 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.