Reaction profile

The FDA adverse-event record for tongue ulceration

271 FDA adverse-event reports reference tongue ulceration (VeDDRA 290). See the species, breeds, and drugs most associated with it below.

271
reports citing this reaction
16.6%
death-coded share
Dog
most-affected species
Robenacoxib
most-associated drug
Verify with FDA CVM →
271
Total Reports
45
Deaths
16.6%
Death Rate

Species Most Affected

Dog 124
Cat 121
Horse 23
Unknown 3

Breeds Most Affected

Domestic Shorthair 71
Cat (unknown) 14
Retriever - Labrador 12
Crossbred Canine/dog 10
Domestic (unspecified) 8
Retriever - Golden 8
Domestic Mediumhair 8
Shepherd Dog - German 7
Domestic Longhair 7
Shih Tzu 6

Associated Drugs

Robenacoxib 31
Meloxicam 23
Carprofen 20
Cefovecin 20
Buprenorphine 20
Isoflurane 18
Maropitant Citrate 17
Enrofloxacin 14
Ketamine 13
Selamectin 9
Prednisone 9
Tigilanol Tiglate 9
Bedinvetmab 9
Deracoxib 8
Butorphanol 8
Fluralaner Chew Tablets 8
Cefovecin Sodium 7
Cyclosporine A 7
Oclacitinib Maleate 7
Dexmedetomidine Hydrochloride 6

Tongue ulceration Reaction Insights

271 reports name Tongue ulceration; 45 recorded a death outcome (16.6% of reported events, not a population-level mortality rate). VeDDRA code: 290.

By species: Dog (124 reports), Cat (121 reports), Horse (23 reports). By breed: Domestic Shorthair (71), Cat (unknown) (14), Retriever - Labrador (12).

Most co-reported drugs: Robenacoxib (31 reports), Meloxicam (23 reports), Carprofen (20 reports), Cefovecin (20 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.