Reaction profile

The FDA adverse-event record for pinnae disorder

344 FDA adverse-event reports reference pinnae disorder (VeDDRA 1985). See the species, breeds, and drugs most associated with it below.

344
reports citing this reaction
3.8%
death-coded share
Dog
most-affected species
Mirtazapine
most-associated drug
Verify with FDA CVM →
344
Total Reports
13
Deaths
3.8%
Death Rate

Species Most Affected

Dog 236
Cat 107
Cattle 1

Breeds Most Affected

Domestic Shorthair 64
Retriever - Labrador 34
Retriever - Golden 16
Shepherd Dog - German 13
Crossbred Canine/dog 12
Boxer (German Boxer) 11
Domestic Longhair 9
Chihuahua 9
Pit Bull 9
Pug 8

Associated Drugs

Mirtazapine 40
Oclacitinib Maleate 34
Maropitant Citrate 23
Milbemycin Oxime + Spinosad 22
Afoxolaner 21
Cefovecin 19
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 19
Selamectin 16
Prednisone 14
Moxidectin 14
Carprofen 14
Gabapentin 14
Sarolaner 12
Anti-Il31 Mab Mcs Lot #1283563 12
Dexamethasone + Neomycin Sulfate + Thiabendazole 11
Betamethasone + Florfenicol + Terbinafine 10
Metronidazole 9
Imidacloprid + Moxidectin 8
Prednisolone 8
Ivermectin + Pyrantel As Pamoate Salt 8

Pinnae disorder Reaction Insights

344 reports name Pinnae disorder; 13 recorded a death outcome (3.8% of reported events, not a population-level mortality rate). VeDDRA code: 1985.

By species: Dog (236 reports), Cat (107 reports), Cattle (1 reports). By breed: Domestic Shorthair (64), Retriever - Labrador (34), Retriever - Golden (16).

Most co-reported drugs: Mirtazapine (40 reports), Oclacitinib Maleate (34 reports), Maropitant Citrate (23 reports), Milbemycin Oxime + Spinosad (22 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.