Reaction profile

The FDA adverse-event record for lack of efficacy (bacteria) - pasteurella multocida

19 FDA reports name lack of efficacy (bacteria) - pasteurella multocida, a lower-volume reaction in the CVM extract (VeDDRA 2997). Plate stamps and neighbourhood peers follow.

#2186 of 2,481
by report volume (all reactions)
19
reports citing this reaction
78.9%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (bacteria) - Pasteurella multocida has 19 reports now versus 18 in that prior snapshot: 1 more (5.6%).

Report change
+1
Death-coded reports
+1
Death-coded share
+1.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (bacteria) - Pasteurella multocida changes

FDA AER · VeDDRA plate

Code 2997 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-MID · BOOK-FULL

  • VOL-TRACE 19 reports
  • DEATH-HOT 78.9%
  • LOWER-Q #2186/2481
  • PHOTO-FINISH Adaptor, damaged
  • SPECIES-CATTLE Cattle · 19
  • DRUG-LEAD Infectious Bovine… · 8
  • DESK-MID 6 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Adaptor, damaged (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy - Pasteurella multocida

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Adaptor, damaged · near19Amaurosis (see also P… · near19Anhidrosis · near19Cholelithiasis · near19Lack of efficacy (bac… · thi…19Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (bacteria) - Pasteurella multocida

Lack of efficacy (bacteria) - Pasteurella multocida: high death-coded share in the FDA AER plate

Signature read: Lack of efficacy (bacteria) - Pasteurella multocida's 78.9% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 19 named reports in the openFDA extract. Death-coded share is upper-third: 15 of 19 reports (78.9% of named reports). Nearest volume peer: Adaptor, damaged (±0 reports). Lead species Cattle (19). Lead co-reported drug Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 19

Breeds Most Affected

Mixed (Cattle) 10
Cattle (other) 5
Crossbred Bovine/Cattle 1
Cattle (unknown) 1
Salers 1
Unknown 1

Associated Drugs

Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus 8
Tulathromycin 8
Bovine Viral Diarrhea Virus, Type 2, Strain 53637, Lot Bvd2Mlv-D;Bovine Viral Di 4
Gamithromycin 4
Ceftiofur Crystalline Free Acid 3
Bovine Viral Diarrhea Virus, Type 1, Strain Nadl-Sbvd, Msvx+1;Bovine Viral Diarr 3
Ketoprofen;Tulathromycin 2
Oxfendazole 2
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid 2
Mycoplasma Bovis 2
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Infectious Bovine Rhinotra 1
Pyramid 5 + Presponse Sq 1
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti 1
Bovine Viral Diarrhea Virus, Type 2, Strain 53637, Lot 062901D;Bovine Viral Diar 1
Micotil 1
Cloxacillin Benzathine 1
Bismuth Subnitrate 60% Intramammary 1
Tilmicosin 1
Oxytetracycline Injection 1
Eprinomectin 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (bacteria) - Pasteurella multocida (#2186 of 2,481 by report volume); death-coded 78.9%. PlainBreed reaction plate · death-coded share stamp 78.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →