Reaction profile

The FDA adverse-event record for chattering of teeth

386 FDA reports name chattering of teeth, a high-volume reaction in the CVM extract (VeDDRA 1072). Plate stamps and neighbourhood peers follow.

#745 of 2,481
by report volume (all reactions)
386
reports citing this reaction
4.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chattering of teeth has 386 reports now versus 382 in that prior snapshot: 4 more (1.0%).

Report change
+4
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chattering of teeth changes

FDA AER · VeDDRA plate

Code 1072 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 386 reports
  • DEATH-LOW 4.9%
  • MID-PACK #745/2481
  • PHOTO-FINISH Confused
  • SPECIES-DOG Dog · 366
  • DRUG-LEAD Afoxolaner · 48
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Confused (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Chattering of teeth

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Confused · near387Chattering of teeth · this r…386Generalised rash · near385PR-HEART, LESION(S) · near385Splenic neoplasm · near385Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Chattering of teeth

Chattering of teeth: low death-coded share in the FDA AER plate

Signature read: Chattering of teeth's 4.9% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 386 named reports in the openFDA extract. Death-coded share is lower-third: 19 of 386 reports (4.9% of named reports). Nearest volume peer: Confused (±1 reports). Lead species Dog (366). Lead co-reported drug Afoxolaner (48).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Afoxolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 366
Cat 18
Rabbit 1
Horse 1

Breeds Most Affected

Retriever - Labrador 59
Crossbred Canine/dog 40
Retriever - Golden 24
Domestic Shorthair 14
Chihuahua 12
Terrier - Yorkshire 12
Terrier - Jack Russell 10
Dog (unknown) 10
Shih Tzu 8
Terrier - Bull - American Pit 8

Associated Drugs

Afoxolaner 48
Pyrantel Pamoate;Sarolaner 46
Sarolaner 32
Milbemycin Oxime + Spinosad 27
Fluralaner Chew Tablets 25
Bedinvetmab 25
Ivermectin + Pyrantel As Pamoate Salt 20
Fluralaner 13.64% 12-Week Chew 19
Trilostane 17
Milbemycin Oxime + Praziquantel 17
Maropitant Citrate 15
Gabapentin 15
Carprofen 13
Spinosad 12
Prednisone 12
Moxidectin 12
Oclacitinib Maleate 12
Selamectin 9
Cyclosporine A 8
Lotilaner 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Chattering of teeth, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (386 here).

Similar death-coded share

Nearest other reactions by death-coded share (4.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chattering of teeth (#745 of 2,481 by report volume); death-coded 4.9%. PlainBreed reaction plate · death-coded share stamp 4.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →