Reaction profile

The FDA adverse-event record for haematemesis

758 FDA adverse-event reports reference haematemesis (VeDDRA 342). See the species, breeds, and drugs most associated with it below.

758
reports citing this reaction
19.3%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
758
Total Reports
146
Deaths
19.3%
Death Rate

Species Most Affected

Dog 686
Cat 70
Human 2

Breeds Most Affected

Retriever - Labrador 88
Crossbred Canine/dog 48
Domestic Shorthair 45
Terrier - Yorkshire 35
Boxer (German Boxer) 27
Shih Tzu 23
Shepherd Dog - German 22
Retriever - Golden 22
Shepherd Dog - Australian 21
Chihuahua 19

Associated Drugs

Carprofen 149
Milbemycin Oxime + Spinosad 79
Moxidectin 66
Maropitant Citrate 65
Afoxolaner 59
Fluralaner Chew Tablets 40
Spinosad 28
Deracoxib 27
Meloxicam 27
Oclacitinib Maleate 27
Famotidine 26
Sucralfate 26
Diphenhydramine Hcl 25
Ivermectin + Pyrantel As Pamoate Salt 24
Grapiprant 22
Butorphanol 21
Gabapentin 20
Firocoxib 20
Isoflurane 18
Imidacloprid + Moxidectin 17

Haematemesis Reaction Insights

758 reports name Haematemesis; 146 recorded a death outcome (19.3% of reported events, not a population-level mortality rate). VeDDRA code: 342.

By species: Dog (686 reports), Cat (70 reports), Human (2 reports). By breed: Retriever - Labrador (88), Crossbred Canine/dog (48), Domestic Shorthair (45).

Most co-reported drugs: Carprofen (149 reports), Milbemycin Oxime + Spinosad (79 reports), Moxidectin (66 reports), Maropitant Citrate (65 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.