Reaction profile

The FDA adverse-event record for quiet

681 FDA adverse-event reports reference quiet (VeDDRA 2645). See the species, breeds, and drugs most associated with it below.

681
reports citing this reaction
15.9%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
681
Total Reports
108
Deaths
15.9%
Death Rate

Species Most Affected

Dog 487
Cat 174
Horse 18
Pig 1
Parrot 1

Breeds Most Affected

Domestic Shorthair 110
Retriever - Labrador 63
Retriever - Golden 35
Crossbred Canine/dog 33
Chihuahua 20
Terrier - Yorkshire 19
Beagle 19
Shepherd Dog - German 15
Shepherd Dog - Australian 14
Shih Tzu 14

Associated Drugs

Maropitant Citrate 86
Buprenorphine 54
Pyrantel Pamoate;Sarolaner 48
Gabapentin 42
Carprofen 41
Sarolaner 39
Bedinvetmab 31
Moxidectin 30
Unspecified 29
Prednisone 28
Afoxolaner 27
Fluralaner 13.64% 12-Week Chew 26
Trilostane 25
Lotilaner 25
Isoflurane 24
Fluid Therapy 24
Milbemycin Oxime + Praziquantel 23
Oclacitinib Maleate 22
Meloxicam 22
Melarsomine Dihydrochloride 20

Quiet Reaction Insights

681 reports name Quiet; 108 recorded a death outcome (15.9% of reported events, not a population-level mortality rate). VeDDRA code: 2645.

By species: Dog (487 reports), Cat (174 reports), Horse (18 reports). By breed: Domestic Shorthair (110), Retriever - Labrador (63), Retriever - Golden (35).

Most co-reported drugs: Maropitant Citrate (86 reports), Buprenorphine (54 reports), Pyrantel Pamoate;Sarolaner (48 reports), Gabapentin (42 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.