Reaction profile

The FDA adverse-event record for neuromuscular disorder nos

186 FDA adverse-event reports reference neuromuscular disorder nos (VeDDRA 1649). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1075 of 2,481
by report volume (all reactions)
186
reports citing this reaction
21.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neuromuscular disorder NOS has 186 reports now versus 185 in that prior snapshot: 1 more (0.5%).

Report change
+1
Death-coded reports
+1
Death-coded share
+0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neuromuscular disorder NOS changes

FDA AER · VeDDRA plate

Code 1649 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 186 reports
  • DEATH-HOT 21.5%
  • MID-PACK #1075/2481
  • PHOTO-FINISH Central nervous syste…
  • SPECIES-DOG Dog · 145
  • DRUG-LEAD Milbemycin Oxime… · 39
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Central nervous system disorder NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Neuromuscular disorder NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cutaneous calcinosis · near187Central nervous syste… · near186Neuromuscular disorde… · thi…186Coughing up blood · near185Epidermal collarette · near185Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Neuromuscular disorder NOS

What the FDA AER plate says about Neuromuscular disorder NOS

Signature read: 40 death-coded reports is a heavy tail count for Neuromuscular disorder NOS in the CVM extract. Report volume sits in the middle third of the reaction corpus. 40 of 186 reports were death-coded (21.5% of named reports, not a population mortality rate). Nearest volume peer: Central nervous system disorder NOS (±0 reports). Lead species Dog (145). Lead co-reported drug Milbemycin Oxime + Spinosad (39).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 145
Cat 26
Turkey 7
Human 3
Chicken 2
Pig 1
Cattle 1
Horse 1

Breeds Most Affected

Domestic Shorthair 16
Retriever - Labrador 13
Boxer (German Boxer) 8
Turkey (unknown) 7
Crossbred Canine/dog 7
Chihuahua 6
Shepherd Dog - German 5
Pit Bull 5
Shih Tzu 5
Terrier (unspecified) 5

Associated Drugs

Milbemycin Oxime + Spinosad 39
Bedinvetmab 24
Sarolaner 13
Carprofen 12
Gabapentin 12
Monensin Sodium 8
Oclacitinib Maleate 8
Spinosad 7
Moxidectin 7
Selamectin 6
Fluralaner Chew Tablets 6
Rabies Vaccine 5
Nitenpyram 5
Ivermectin + Pyrantel As Pamoate Salt 5
Prednisone 5
Cefovecin 5
Tramadol 5
Grapiprant 5
Afoxolaner 4
Isoflurane 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Neuromuscular disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (21.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neuromuscular disorder NOS (#1075 of 2,481 by report volume); death-coded 21.5%. PlainBreed reaction plate · death-coded report count stamp 40 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →