Reaction profile

The FDA adverse-event record for peeling skin

283 FDA adverse-event reports reference peeling skin (VeDDRA 944). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#897 of 2,481
by report volume (all reactions)
283
reports citing this reaction
9.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Peeling skin has 283 reports now versus 283 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Peeling skin changes

FDA AER · VeDDRA plate

Code 944 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 283 reports
  • DEATH-PAR 9.5%
  • MID-PACK #897/2481
  • PHOTO-FINISH Cardiomyopathy
  • SPECIES-DOG Dog · 174
  • DRUG-LEAD Milbemycin Oxime… · 21
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cardiomyopathy (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Peeling skin

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cardiomyopathy · near283Cognitive disorder NOS · near283Injection site serosa… · near283Lack of efficacy (fun… · near283Peeling skin · this reaction283Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Peeling skin

What the FDA AER plate says about Peeling skin

Signature read: report volume at 283 (#897 of 2,481) is the standout scale stamp on Peeling skin. Report volume sits in the middle third of the reaction corpus. 27 of 283 reports were death-coded (9.5% of named reports, not a population mortality rate). Nearest volume peer: Cardiomyopathy (±0 reports). Lead species Dog (174). Lead co-reported drug Milbemycin Oxime + Spinosad (21).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 174
Cat 63
Human 23
Horse 16
Cattle 6
Fish 1

Breeds Most Affected

Domestic Shorthair 39
Unknown 27
Crossbred Canine/dog 15
Chihuahua 13
Retriever - Labrador 10
Domestic (unspecified) 9
Terrier - Boston 6
Retriever - Golden 6
Dog (unknown) 5
Quarter Horse 5

Associated Drugs

Milbemycin Oxime + Spinosad 21
Trilostane 20
Selamectin 16
Oclacitinib Maleate 16
Afoxolaner 15
Prednisone 13
Carprofen 10
Cefovecin 10
Buprenorphine 9
Cefovecin Sodium 8
Cyclosporine 7
Mirtazapine 7
Fluralaner Chew Tablets 7
Ivermectin + Pyrantel As Pamoate Salt 7
Emodepside + Praziquantel 6
Imidacloprid + Moxidectin 6
Moxidectin 6
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 6
Cephalexin 6
Sarolaner 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Peeling skin, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Peeling skin (#897 of 2,481 by report volume); death-coded 9.5%. PlainBreed reaction plate · report volume stamp 283 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →