Reaction profile

The FDA adverse-event record for breathlessness

120 FDA adverse-event reports reference breathlessness (VeDDRA 1915). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1300 of 2,481
by report volume (all reactions)
120
reports citing this reaction
26.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Breathlessness has 120 reports now versus 120 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Breathlessness changes

FDA AER · VeDDRA plate

Code 1915 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 120 reports
  • DEATH-HOT 26.7%
  • MID-PACK #1300/2481
  • PHOTO-FINISH Burn
  • SPECIES-DOG Dog · 90
  • DRUG-LEAD Milbemycin Oxime… · 22
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Burn (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Breathlessness

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Breathlessness · this reacti…120Burn · near120Groaning · near120Neck pain - neurologi… · near120Reduced food intake · near120Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Breathlessness

Breathlessness: high death-coded share in the FDA AER plate

Signature read: Breathlessness's 26.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 32 of 120 reports (26.7% of named reports). Nearest volume peer: Burn (±0 reports). Lead species Dog (90). Lead co-reported drug Milbemycin Oxime + Spinosad (22).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 90
Human 17
Cat 12
Pig 1

Breeds Most Affected

Unknown 18
Chihuahua 7
Crossbred Canine/dog 7
Retriever - Labrador 6
Terrier - Yorkshire 6
Domestic Shorthair 6
Pug 4
Boxer (German Boxer) 4
Beagle 3
Shepherd Dog - German 3

Associated Drugs

Milbemycin Oxime + Spinosad 22
Buprenorphine 8
Afoxolaner 7
Bedinvetmab 7
Spinosad 6
Isoflurane 6
Trilostane 6
Fluralaner 13.64% 12-Week Chew 5
Carprofen 4
Maropitant Citrate 4
Nitenpyram 4
Fluralaner Chew Tablets 4
Ivermectin + Pyrantel As Pamoate Salt 4
Afoxolaner 136 Mg Chewable Tablets 4
Butorphanol 4
Ketamine 4
Propofol 4
Dexmedetomidine 4
Tilmicosin Phosphate 3
Selamectin 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Breathlessness, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (120 here).

Similar death-coded share

Nearest other reactions by death-coded share (26.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Breathlessness (#1300 of 2,481 by report volume); death-coded 26.7%. PlainBreed reaction plate · death-coded share stamp 26.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →