Reaction profile

The FDA adverse-event record for impaired swallowing

95 FDA adverse-event reports reference impaired swallowing (VeDDRA 284). See the species, breeds, and drugs most associated with it below.

95
reports citing this reaction
36.8%
death-coded share
Dog
most-affected species
Imidacloprid + Moxidectin
most-associated drug
Verify with FDA CVM →
95
Total Reports
35
Deaths
36.8%
Death Rate

Species Most Affected

Dog 55
Cat 37
Horse 3

Breeds Most Affected

Domestic Shorthair 24
Retriever - Labrador 11
Maine Coon 4
Terrier - Yorkshire 3
Domestic Mediumhair 3
Mixed (Dog) 3
Crossbred Canine/dog 3
Terrier - Boston 2
Thoroughbred 2
Domestic Longhair 2

Associated Drugs

Imidacloprid + Moxidectin 8
Selamectin 8
Milbemycin Oxime + Spinosad 7
Enrofloxacin 7
Bedinvetmab 6
Afoxolaner 5
Eprinomectin + Esafoxolaner + Praziquantel 5
Spinosad 4
Cefovecin 4
Prednisone 4
Meloxicam 4
Fluralaner 13.64% 12-Week Chew 4
Metronidazole 3
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 3
Ivermectin 3
Diazepam 3
Phenobarbital 3
Dexamethasone 3
Carprofen 3
Fluralaner Spot-On Solution 3

Impaired swallowing Reaction Insights

95 reports name Impaired swallowing; 35 recorded a death outcome (36.8% of reported events, not a population-level mortality rate). VeDDRA code: 284.

By species: Dog (55 reports), Cat (37 reports), Horse (3 reports). By breed: Domestic Shorthair (24), Retriever - Labrador (11), Maine Coon (4).

Most co-reported drugs: Imidacloprid + Moxidectin (8 reports), Selamectin (8 reports), Milbemycin Oxime + Spinosad (7 reports), Enrofloxacin (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.