Gastric ulceration NOS

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VeDDRA Code: 1489

250 adverse event reports referencing this reaction

250
Total Reports
75
Deaths
3000.0%
Death Rate

Species Most Affected

Dog 180
Horse 57
Cat 5
Cattle 3
Human 1
Chicken 1
Rabbit 1
Other Rodents 1
Mouse 1

Breeds Most Affected

Retriever - Labrador 30
Dog (unknown) 17
Quarter Horse 13
Thoroughbred 11
Horse (unknown) 11
Crossbred Canine/dog 9
Shih Tzu 7
Rottweiler 6
Terrier - Yorkshire 5
Retriever - Golden 5

Associated Drugs

Carprofen 49
Omeprazole 37% Oral Paste 47
Meloxicam 29
Maropitant Citrate 25
Firocoxib 19
Deracoxib 19
Grapiprant 18
Gabapentin 17
Buprenorphine 11
Milbemycin Oxime + Spinosad 10
Sucralfate 10
Trilostane 10
Oclacitinib Maleate 9
Afoxolaner 8
Firocoxib 227 Mg Chewable 7
Famotidine 7
Enrofloxacin 7
Prednisone 7
Omeprazole 6
Doxycycline 6

Data Summary

Metric Value
Total reports referencing reaction 250
Reports with fatal outcome 75
Case-fatality rate (reported events) 3000.0%
Species observed 9
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1489.

Gastric ulceration NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 250 adverse event reports that reference Gastric ulceration NOS as a reaction term, including 75 reports with a death outcome — a 3000.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1489, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Gastric ulceration NOS appears most frequently in reports for Dog (180 reports), Horse (57 reports), Cat (5 reports) — with Dog dominating at 180 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (30), Dog (unknown) (17), Quarter Horse (13). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Gastric ulceration NOS are Carprofen (49 reports), Omeprazole 37% Oral Paste (47 reports), Meloxicam (29 reports), Maropitant Citrate (25 reports), with Carprofen appearing alongside this reaction in 49 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial