Reaction profile

The FDA adverse-event record for self mutilation

211 FDA adverse-event reports reference self mutilation (VeDDRA 1222). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1006 of 2,481
by report volume (all reactions)
211
reports citing this reaction
5.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Self mutilation has 211 reports now versus 209 in that prior snapshot: 2 more (1.0%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Self mutilation changes

FDA AER · VeDDRA plate

Code 1222 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 211 reports
  • DEATH-PAR 5.2%
  • MID-PACK #1006/2481
  • PHOTO-FINISH Chewing - oral cavity…
  • SPECIES-DOG Dog · 127
  • DRUG-LEAD Milbemycin Oxime… · 34
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Chewing - oral cavity disorder (see also 'Pruritus') (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Self mutilation

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Chewing - oral cavity… · near211Hyperadrenocorticism · near211Opisthotonus · near211Self mutilation · this react…211Skin haemorrhage NOS · near211Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Self mutilation

Self mutilation: low death-coded share in the FDA AER plate

Signature read: Self mutilation's 5.2% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 11 of 211 reports (5.2% of named reports). Nearest volume peer: Chewing - oral cavity disorder (see also 'Pruritus') (±0 reports). Lead species Dog (127). Lead co-reported drug Milbemycin Oxime + Spinosad (34).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 127
Cat 81
Horse 1
Parrot 1
Rat 1

Breeds Most Affected

Domestic Shorthair 38
Retriever - Labrador 16
Domestic (unspecified) 15
Domestic Mediumhair 9
Pit Bull 6
Chihuahua 6
Shih Tzu 6
Terrier - Yorkshire 5
Crossbred Canine/dog 5
Domestic Longhair 5

Associated Drugs

Milbemycin Oxime + Spinosad 34
Spinosad 27
Selamectin 25
Afoxolaner 23
Frunevetmab 12
Fluralaner Spot-On Solution 9
Prednisone 6
Carprofen 6
Gabapentin 5
Selamectin;Sarolaner 5
Enrofloxacin 4
Cyclosporine 4
Moxidectin 4
Imidacloprid + Moxidectin 4
Cefovecin 4
Nitenpyram 4
Oclacitinib Maleate 4
Melarsomine Dihydrochloride 3
Ivermectin 3
Ivermectin + Pyrantel As Pamoate Salt 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Self mutilation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (5.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Self mutilation (#1006 of 2,481 by report volume); death-coded 5.2%. PlainBreed reaction plate · death-coded share stamp 5.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →