Reaction profile

The FDA adverse-event record for lack of heart sounds on auscultation

Name: Lack of heart sounds on auscultation - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

21 FDA reports name lack of heart sounds on auscultation, a lower-volume reaction in the CVM extract (VeDDRA 2839). Plate stamps and neighbourhood peers follow.

#2144 of 2,481
by report volume (all reactions): 21
reports citing this reaction: 61.9%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of heart sounds on auscultation has 21 reports now versus 21 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of heart sounds on auscultation changes

FDA AER · VeDDRA plate

Code 2839 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 21 reports
DEATH-HOT 61.9%
LOWER-Q #2144/2481
PHOTO-FINISH Chewing - pruritus
SPECIES-DOG Dog · 18
DRUG-LEAD Bedinvetmab · 8
DESK-WIDE 13 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Chewing - pruritus (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of heart sounds on auscultation

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Lack of heart sounds on auscultation

Lack of heart sounds on auscultation: high death-coded share in the FDA AER plate

Signature read: Lack of heart sounds on auscultation's 61.9% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 21 named reports in the openFDA extract. Death-coded share is upper-third: 13 of 21 reports (61.9% of named reports). Nearest volume peer: Chewing - pruritus (±0 reports). Lead species Dog (18). Lead co-reported drug Bedinvetmab (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 18

Cat 3

Breeds Most Affected

Retriever - Labrador 6

Retriever - Golden 2

Domestic Shorthair 2

Terrier - Bull - American Pit 2

Terrier (unspecified) 1

Sheepdog - Shetland 1

Retriever - Flat-coated 1

Norwegian Forest 1

Collie - Border 1

Shepherd Dog - Australian 1

Associated Drugs

Bedinvetmab 8

Carprofen 5

Gabapentin 5

Medetomidine Hydrochloride, Vatinoxan Hydrochloride 3

Butorphanol Tartrate 2

Isoflurane 2

Moxidectin 2

Maropitant Citrate 2

Galliprant 2

Hydromorphone 2

Dexmedetomidine Hydrochloride Injection 1

Butorphanol Tartrate Injection 1

Sevoflourane 1

Atipamezole 1

Intravenous Fluids 1

Robenacoxib 1

Buprenorphine 1

Xylazine 1

Ketamine 1

Grapiprant 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of heart sounds on auscultation (#2144 of 2,481 by report volume); death-coded 61.9%. PlainBreed reaction plate · death-coded share stamp 61.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →