Reaction profile

The FDA adverse-event record for pancreas endocrine disorder nos

33 FDA reports name pancreas endocrine disorder nos, a lower-volume reaction in the CVM extract (VeDDRA 396). Plate stamps and neighbourhood peers follow.

#1946 of 2,481
by report volume (all reactions)
33
reports citing this reaction
54.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pancreas endocrine disorder NOS has 33 reports now versus 33 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pancreas endocrine disorder NOS changes

FDA AER · VeDDRA plate

Code 396 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 33 reports
  • DEATH-HOT 54.5%
  • LOWER-Q #1946/2481
  • PHOTO-FINISH Abnormal dexamethason…
  • SPECIES-DOG Dog · 23
  • DRUG-LEAD Afoxolaner · 6
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal dexamethasone suppression test (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Pancreas endocrine disorder NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal dexamethason… · near33Burning mouth sensati… · near33Decreased number of s… · near33Displaced abomasum · near33Pancreas endocrine di… · thi…33Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pancreas endocrine disorder NOS

Pancreas endocrine disorder NOS: high death-coded share in the FDA AER plate

Signature read: Pancreas endocrine disorder NOS's 54.5% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 33 named reports in the openFDA extract. Death-coded share is upper-third: 18 of 33 reports (54.5% of named reports). Nearest volume peer: Abnormal dexamethasone suppression test (±0 reports). Lead species Dog (23). Lead co-reported drug Afoxolaner (6).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 23
Cat 10

Breeds Most Affected

Domestic Shorthair 4
Rottweiler 2
Shepherd Dog - German 2
Schnauzer - Miniature 2
Retriever - Golden 2
Domestic Mediumhair 2
Collie - Border 2
Setter - Irish Red 1
Retriever - Labrador 1
Pit Bull 1

Associated Drugs

Afoxolaner 6
Milbemycin Oxime + Spinosad 4
Maropitant Citrate 4
Ivermectin + Pyrantel As Pamoate Salt 3
Carprofen 2
Rabies Vaccine 2
Prednisone 2
Emodepside + Praziquantel 2
Fluids 2
Spinosad 2
Meloxicam 2
Ivermectin 1
Spinosad; Milbemycin Oxime 1
Fish Oil 1
Trilostane 1
Vetsulin 1
Cefovecin 1
Imidacloprid + Moxidectin 1
Unknown Antibiotic 1
Unspecified Shampoo 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pancreas endocrine disorder NOS (#1946 of 2,481 by report volume); death-coded 54.5%. PlainBreed reaction plate · death-coded share stamp 54.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →